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No Association Between Vitiligo and Obesity: A Case-control Study

Conclusion: In this study, vitiligo did not appear to be associated with a high body mass index: obesity might not be a risk factor for vitiligo, in contrast to most autoimmune diseases which are significantly associated with obesity.
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research

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Authors: Zang H, Jiang F, Cheng X, Xu H, Hu X Abstract Adropin has been identified as potent regulatory hormone implicated in insulin sensitivity and the maintenance of energy homeostasis. The aim of current study was to investigate serum adropin concentrations of type 2 diabetes mellitus (T2DM) patients in the fasting status, especially those overweight/obese and evaluate the relationships between adropin levels and metabolic parameters. A total of 116 T2DM patients and 60 controls with normal glucose tolerance (NGT) were recruited to the study. Adropin concentration was determined using commercial ELISA kits. Ant...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
We described sociodemographic and health risk factors of each phenotype and then applied logistic and ordinal regression models to identify associated risk factors and level of severity of the phenotypes. RESULTS: Among 4,427 children with asthma in this NSCH cohort, the association between race and phenotype is statistically significant (p
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
We present the case of a 68-year-old woman with combined antiphospholipid syndrome and factor XI deficiency, with chronic prolongation of activated partial thromboplastin time that was not correctable with fresh-frozen plasma (FFP).The patient had a history of stroke, but was not on antiplatelet therapy because of mucocutaneous bleeding events. She had progressive renal failure attributed to her autoimmune disease, and a decision was made to pursue peritoneal dialysis (PD) when she reached end-stage kidney disease. She was admitted to the hospital the day before her planned PD catheter placement and was transfused with FFP...
Source: Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis - Category: Urology & Nephrology Tags: Adv Perit Dial Source Type: research
AbstractThe purpose of this investigation was to determine the effects of 28  weeks of high-intensity interval training (HIIT) during physical education classes on the weight status, cardiorespiratory capacity, and blood pressure of overweight and obese schoolchildren. The participants included 197 schoolchildren (108 girls and 89 boys) aged between 6 and 11 years (8.39  ± 1.15 years) in four groups: experimental group 1 (EG1) = 59 overweight schoolchildren; experimental group 2 (EG2) = 92 obese schoolchildren; control group 1 (CG1) = 17 overweig...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
The objective of this study was to assess CRP on POD1 as a predictor for early IAI (within 7  days following surgery) in patients after laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (LRYGB).MethodsPatients with bariatric surgery between 08/2010 and 06/2017 were included. The predictive capacity of CRP for early IAI was determined using a receiver operating characteristics (ROC) analysis.ResultsIn 523 patients (68.5% female, LSG  = 358, LRYGB = 165), 16 (3%) early IAI were observed. ROC analysis revealed a significant predictive capacity of POD1 CRP for early IAI, with a...
Source: Obesity Surgery - Category: Surgery Source Type: research
Africa ’s attempts to achieve health for all by 2030 could be threatened unless the continent address the twin challenges of undernutrition and obesity, experts attending a United Nations meeting in Nairobi this week have warned.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news
The finding by Remmler et  al1 that increased levels of interleukin 6 (IL6) predict 90-day and 1-year mortality in patients with end-stage liver disease is of high importance. In addition to its relevance for prognosis and timing of liver transplantation, we believe that the determination of IL6 levels could represent a pos sible target for therapy. Indeed, IL6 increases occur in autoimmune diseases, but more importantly is a consequence of infections. Viral causes of chronic liver diseases, such as hepatitis C and B viruses, now can be cured in a very high percentage of patients with the administration of antivirals.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
CONCLUSION: Decreased SpO2 was a significant predictor of abnormal mitral Doppler flow. Diastolic dysfunction should be considered when SpO2 ≤ 95% is found. PMID: 29671629 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
DISCUSSION: Five studies met the inclusion criteria and were included in the systematic review. The average Jadad score was 1, the average level of evidence 3. In two studies, infection and revision occured more often in obese patients. Patients with morbid obesity had a higher risk of wound revision and periprosthetic joint infections. Three studies showed that obese patients had significantly lower scores for clinical outcome measures in function and pain. The legal aspect was not discussed in any of the five studies. Overall, published data are sparse and very heterogeneous. Therefore comparing these five studies is dif...
Source: Zeitschrift fur Orthopadie und Unfallchirurgie - Category: Orthopaedics Tags: Z Orthop Unfall Source Type: research
Conclusion: Vitiligo patients showed a better lipid profile, with higher levels of high-density lipoprotein cholesterol and lower TGs and WC values. In patients with vitiligo, increased insulin levels and insulin resistance may be related to other mechanisms than obesity, such as production of cytokines or autoimmune reaction to melanocytes. Further large-scale studies are needed to confirm these findings.
Source: Journal of the Egyptian Women’s Dermatologic Society - Category: Dermatology Tags: Original articles Source Type: research
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