Submillisievert imaging protocol using full reconstruction and advanced patient motion correction in 320-row area detector coronary CT angiography

AbstractRadiation exposure remains a concern in the use of coronary CT angiography (CCTA). Full reconstruction (Full) and reconstruction using advanced patient motion correction (APMC) could obtain a lower radiation dose using low tube current scanning in a 320-row Area Detector CT (320-ADCT). The radiation dose for an imaging protocol using Full and APMC in daily practice was estimated. A total of 209 patients who underwent CCTA in 1 rotation scanning with 100 kv and adaptive iterative dose reduction 3D in 320-ADCT were enrolled. Imaging protocols were classified into 3 groups based on estimated slow filling time: (1) slow filling time  ≥ 275 msec, Full with 30% of usual tube current (N = 43)(Full30%mA) (2) 206.3 msec ≤ slow filling time <  275 msec, APMC with 50% of usual tube current (N = 48)(APMC50%mA); and (3) 137.5 msec ≤ slow filling time <  206.3 msec, Half reconstruction with usual tube current (N = 118)(Half100%mA). Radiation dose was estimated by the effective dose. The diagnostic accuracy of CCTA was compared with that of invasive coronary angiography in 28 patients. The effective doses of Full30%mA, APMC50%mA, and Half100% mA were 0.77 ± 0.31, 1.30 ± 0.85, and 1.98 ± 0.68, respectively. Of 28 patients, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value in vessel-based analyses were: Full30%mA, 66.7, 82.4, 80.0, 40.0, and 93.3%; APMC50%mA, 100.0, 80.0, 83.3,...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research