Offset analgesia: The role of peripheral and central mechanisms

ConclusionThis study showed that OA could be elicited when the stimuli were applied both to the same and to different locations (ipsi‐ and contralateral) indicating that peripheral as well as central mechanisms are involved in mediating OA. SignificanceThis study investigated offset analgesia by applying thermal painful stimuli to the ipsi‐ and bilateral forearms in healthy subjects and found that both peripheral and central mechanisms seem to mediate offset analgesia.
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: Original Article Source Type: research