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Effect of the cellular and humoral immune response in infertile couples and its relationship with infections.

[Effect of the cellular and humoral immune response in infertile couples and its relationship with infections.] Arch Esp Urol. 2017 Sep;70(7):662-668 Authors: Brufman A, Colombo L, Streiger E, Pusillico R Abstract OBJECTIVE: The purpose of this study was to determine the prevalence of different microorganisms isolated from the urogenital tract of infertile men and assess whether there are differences in semen parameters according to the presence or absence of genital infections. METHODS: 280 semen samples from infertile men were studied retrospectively. Semen parameters were analyzed according to the World Health Organization criteria (WHO 2010). Microbiological analysis was performed using the modified method of Stamey and Meares proposed by Santoianni et al. RESULTS: Microbiological studies showed absence of microorganisms or presence of usual colonizing flora in 67.86% of the samples (GROUP 1) and presence of at least one pathogen or potential pathogen in 32.14% (GROUP 2). No significant differences in ejaculate volume (p=0.353), pH value (p=0.801), motility (p>0.30), citric acid concentration (p=0.383) and viscosity (p=0.948) were observed between the two groups. The relative sperm count was significantly lower in infected patients than in those without pathogens (p=0.05). Teratozoospermia index (TZI) was evaluated. Samples of infected patients showed TZI values higher than patients without microorganisms or normal genital tract flora (p
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

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CONCLUSION: CD was not more common in women with unexplained infertility than those with an identifiable cause of infertility. These results do not support the routine screening of Canadian women with infertility for CD. PMID: 29132967 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
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Source: BMC Women's Health - Category: OBGYN Authors: Tags: Research article Source Type: research
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Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Funding Opportunity PA-18-093 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of oocyte mitochondrial function in relation to fertility, aging, and mitochondrial disease transmission to offspring. The overarching goal is to gain fundamental insight into the role of mitochondria and long-term consequences of their dysfunction in the oocyte, and to develop therapeutic or alternative approaches to treat mitochondrial dysfunction for improving oocyte quality and compete...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
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Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Many doctors routinely do a laparoscopy and hysteroscopy for all infertile women.They justify this by saying it's a simple diagnostic procedure, which will allow them to confirm that there is no anatomical problem.They also say it's "minor surgery", which just involves a "small cut" and a few hours stay in a hospital.What they don't tell the patient that there's absolutely no need to do a laparoscopy at all ! Let's not forget that the safest surgery is the one you don't need to do !The truth is that laparoscopy does not provide us with any useful information which we cannot obtain with simpler non-invas...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
As The Author of Minding Our Elders: Caregivers Share Their Personal Stories, I'm honored to be chosen to be part AlzAuthors. This post is courtesy of AlzAuthors. Read through for some incredible deals on ebooks written by authors who've been where you are. MOE is among the books on sale. All are $2.99 or less. November is National Caregiver Appreciation Month, a time to recognize the long hours, sacrifice, and love all caregivers bring to the task of caring for a loved one with dementia or any long-term illness. In honor of their efforts, AlzAuthors is hosting an eBook sale and giveaway! This is a terrific way f...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
ConclusionsThe higher levels of intracellular ROS and DNA fragmentation in the semen samples of unexplained infertile couples and their causes might be considered as an important factor related to diagnosis and treatment of the unexplained infertile couples.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
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Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
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