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CPAP or NIV in Obesity Hypoventilation Syndrome CPAP or NIV in Obesity Hypoventilation Syndrome

The preferred mode of respiratory support for obesity hypoventilation syndrome remains controversial.Thorax
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

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Skeletal muscle is a key organ in energy homeostasis owing to its high requirement for nutrients. Heterotrimeric G proteins converge signals from cell-surface receptors to potentiate or blunt responses against environmental changes. Here, we show that muscle-specific ablation of Gα13 in mice promotes reprogramming of myofibers to the oxidative type, with resultant increases in mitochondrial biogenesis and cellular respiration. Mechanistically, Gα13 and its downstream effector RhoA suppressed nuclear factor of activated T cells 1 (NFATc1), a chief regulator of myofiber conversion, by increasing Rho-associated ki...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
BOSTON (CBS) – Researchers at Columbia University Medical Center and the University of North Carolina have developed a new way to get rid of “love handles” at least in rodents. Using a skin patch loaded with microneedles, researchers were able to deliver drugs painlessly into the tissue below, converting white fat into brown fat. Brown fat, which helps keep babies warm, is metabolically active and rather than storing fat, it can burn fat. In experiments with obese mice, the patch reduced the fat underneath by 20% in a week. The hope is that one day the patch could treat fat pockets like “love handle...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Local Syndicated Local Dr. Mallika Marshall Source Type: news
ConclusionsOral treatment with roflumilast in rats fed an HFD restores normal bladder function and downregulates expression of inflammatory factors in the bladder.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionHepatitis C infection, obesity, being elderly, and having long hemodialysis period reduced the hepatitis B vaccination response in hemodialysis patients.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
Conclusions: We classified p,p′-DDT and p,p′-DDE as “presumed” to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527 Received: 17 May 2016 Revised: 04 May 2017 Accepted: 09 May 2017 Published: 18 September 2017 Please address correspondence to M.A. La Merrill, Dept. of Environmental Toxicology, University of California, Davis, 1 Shields Ave., 4245 Meyer Hall, Davis, CA 95616-5270 USA. Telephone: (530) 754-7254. E...
Source: EHP Research - Category: Environmental Health Authors: Tags: Review Source Type: research
There are multiple factors that contribute to childhood obesity, including a clear genetic component, say two Yale experts.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news
October 12, 2017 2:00-3:30pm ET.
Source: HSR Information Central - Category: International Medicine & Public Health Source Type: news
Conclusion: LPA is able to interrupt insulin signaling in primary rat hepatocytes via the LPA3 receptor subtype. Moreover, the bioactive lipid LPA (16: 0) is increased in obesity.Cell Physiol Biochem 2017;43:445 –456
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Summary Excess sugar intake increases risk for obesity and related comorbidities among children. The World Health Organization (WHO), American Heart Association (AHA) and the 2015 USDA dietary recommendations have proposed guidelines for added sugar intake to reduce risk for disease. WHO and USDA recommendations are presented as a percentage of daily calories from added sugar. This approach is not easily understood or translated to children, where energy needs increase with age. The AHA recommendation is based on a fixed value of 25 g of added sugar for all children 2–19 years of age. This approach does not...
Source: Pediatric Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Short Communication Source Type: research
Researchers reveal how a drug-loaded skin patch reduced 'love handles' and fasting blood glucose levels in obese mice by increasing fat browning.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news
More News: Eating Disorders & Weight Management | Health | Obesity | Respiratory Medicine