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An up-down determination of the required seated duration after intrathecal injection of bupivacaine and fentanyl for the prevention of hypotension during Cesarean delivery

AbstractPurposeA prolonged seated time after intrathecal injection of hyperbaric bupivacaine and morphine is related to the incidence of hypotension during Cesarean delivery, but results in a high incidence of pain during peritoneal closure. We conducted this study to determine the effect of the addition of intrathecal fentanyl on the relationship between seated time and hypotension and intraoperative analgesia requirements.MethodsWomen undergoing Cesarean delivery were randomized to receive an intrathecal injection of either 11.25 or 15 mg of hyperbaric bupivacaine with morphine 150 µg and fentanyl 15 µg using a combined spinal-epidural technique. The seated duration following intrathecal injection was assigned using up-down methodology. If the preceding patient was hypo- or normotensive, the next patient sat for 15 sec more or less, respectively. A systolic blood pressure
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research

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Authors: Tarıkçı Kılıç E, Aydın G Abstract BACKGROUND: We evaluated the effects of intravenous dexmedetomidine during spinal anesthesia on hemodynamics, respiratory rate, oxygen saturation, sedpain, and compared them with those of saline infusion. Sixty American Society of Anesthesiologists physical status I and II cases were randomly divided into two groups. Patients were connected to the monitor after premedication, and spinal anesthesia was administered. Sensory and motor blockades were assessed using pinprick test and Bromage scale, respectively. Group I received dexmedetomidine infusion and ...
Source: Libyan Journal of Medicine - Category: General Medicine Tags: Libyan J Med Source Type: research
ConclusionsThe ESP block may be a promising alternative to other interventional procedures in the management of chronic shoulder pain and deserves further study.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research
Background Early postoperative ambulation is associated with enhanced functional recovery, particularly in the postpartum population, but ambulation questionnaires are limited by recall bias. This observational study aims to objectively quantify ambulation after neuraxial anesthesia and analgesia for cesarean delivery and vaginal delivery, respectively, by using activity tracker technology. The hypothesis was that vaginal delivery is associated with greater ambulation during the first 24  h postdelivery, compared to cesarean delivery.Methods Parturients having first/second cesarean delivery under spinal anesthesia o...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Background Peripheral nociceptors expressing the ion channel transient receptor potential cation channel, subfamily V, member 1, play an important role in mediating postoperative pain. Signaling from these nociceptors in the peri- and postoperative period can lead to plastic changes in the spinal cord and, when controlled, can yield analgesia. The transcriptomic changes in the dorsal spinal cord after surgery, and potential coupling to transient receptor potential cation channel, subfamily V, member 1 –positive nociceptor signaling, remain poorly studied.Methods Resiniferatoxin was injected subcutaneously into rat hi...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 13 February 2018 Source:Anaesthesia Critical Care & Pain Medicine Author(s): Sevim Cesur, Ayse Nur Ay, Murat Yayik, M.Emin Naldan, Yavuz Gurkan
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Condition:   Pain, Postoperative Interventions:   Drug: 30 mg Paracetamol 3% (1 mL);   Drug: 60 mg Paracetamol 3% (2 mL);   Drug: 90 mg Paracetamol 3% (3 mL);   Drug: Placebo, 0.9% saline solution;   Drug: NIMP: Chloroprocaine HCl 1% (10 mg/mL), solution for injection Sponsors:   Sintetica SA;   Cross Research S.A. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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