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OCT Screening Cost-effective for Diabetic Retinopathy OCT Screening Cost-effective for Diabetic Retinopathy

It might make sense to screen everyone with diabetes for retinopathy using optical coherence tomography (OCT), new research suggests.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

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New research presented at the annual meeting of the American Society of Anesthesiologists suggests that older patients with diabetes are 84% more likely to develop postoperative cognitive dysfunction.News Medical
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
ConclusionsThese simulated complication rates might help inform the degree to which complications might be reduced by targeting particular HbA1c reductions in Type 2 diabetes.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - Category: Endocrinology Authors: Tags: Research Article Source Type: research
DIABETES sufferers are at an increased risk of heart disease and stroke. But now research has also revealed they are more likely to develop cognitive dysfunction - including problems with thinking and remembering - after surgery.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
TAKING antibiotics when you don ’t need them could one day mean antibiotics resistance is a bigger killer than cancer and diabetes combined, say experts.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
A new study examines the impacts of NAFLD on endothelial function and the risk for subclinical atherosclerosis among obese Hispanic adolescents.Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
(Medical College of Georgia at Augusta University) A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis. The enzyme is protein disulfide isomerase, or PDI, and there's increasing evidence that it is essential to the healthy remodeling of the endothelial cells that line our blood vessels and to the production of new blood vessels when we need them.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
AbstractPurpose of ReviewType 2 diabetes (T2D) is a complex genetic metabolic disorder. T2D heritability has been estimated around 40 –70%. In the last decade, exponential progress has been made in identifying T2D genetic determinants, through genome-wide association studies (GWAS). Among single-nucleotide polymorphisms mostly associated with T2D risk, rs10830963 is located in theMTNR1B gene, encoding one of the two receptors of melatonin, a neurohormone involved in circadian rhythms. Subsequent studies aiming to disentangle the role ofMTNR1B in T2D pathophysiology led to controversies. In this review, we will tackle...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
AbstractPurpose of ReviewIn this article, we examine the nature of the complex relationship between insulin and cardiovascular disease. With metabolic abnormalities comes increased risk for cardiovascular complications. We discuss the key factors implicated in development and progression of cardiovascular disease, its relationship to insulin therapy, and what can be learned from large, recent cardiovascular outcome studies.Recent FindingsPreclinical studies suggest that insulin has positive effects of facilitating glucose entry into cells and maintaining euglycemia and negative effects of favoring obesity and atherogenesis...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
AbstractPurpose of ReviewSulfonylureas (SUs) are one of the most commonly used glucose-lowering agents worldwide. While their efficacy is undisputed, their cardiovascular safety has been debated since the 1970 ’s.Recent FindingsWith no dedicated cardiovascular studies to definitively answer this question, observational studies and meta-analyses abound and have reported divergent results, fueling the controversy. Studies that compared SUs to metformin or newer agents, like GLP-1 agonists and SGLT2 inhibitors, suggest a difference in cardiovascular events, yet this is likely the result of beneficial effects of the latt...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
AbstractPurpose of ReviewThis review summarizes the current knowledge on the relationship of physical activity, exercise, and cardiorespiratory fitness (CRF) with cardiovascular autonomic neuropathy (CAN) based on epidemiological, clinical, and interventional studies.Recent FindingsThe prevalence of CAN increases with age and duration of diabetes. Further risk factors for CAN comprise poor glycemic control, dyslipidemia, abdominal obesity, hypertension, and the presence of diabetic complications. CAN has been also linked to reduced CRF. We recently showed that CRF parameters (e.g., maximal oxidative capacity or oxidative c...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
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