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A. tabacinus

Species
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Mon, 09/18/2017 - 15:12News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Conclusions: A precise and highly sensitive liquid chromatography-tandem mass spectrometry method was developed that enables quantification of triazoles in plasma and serum matrix across therapeutically relevant concentration ranges. It was successfully implemented in our therapeutic drug monitoring routine service and is suitable for routine monitoring of antifungal therapy and in severely ill patients.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Original Article Source Type: research
er O Abstract The incidence of azole resistance in Aspergillus species has increased over the past years, most importantly for Aspergillus fumigatus. This is partially attributable to the global spread of only a few resistance alleles through the environment. Secondary resistance is a significant clinical concern, as invasive aspergillosis with drug-susceptible strains is already difficult to treat, and exclusion of azole-based antifungals from prophylaxis or first-line treatment of invasive aspergillosis in high-risk patients would dramatically limit drug choices, thus increasing mortality rates for immunocomprom...
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
In this study, high-throughput RNA-seq was used to investigate salt stress-induced genes in the parent, ΔcnaB, and ΔcnaBΔcchA strains of Aspergillus nidulans, which differ greatly in salt adaption. In total, 2,884 differentially expressed genes including 1,382 up- and 1,502 downregulated genes were identified. Secondary transporters, which were upregulated to a greater extent in ΔcnaBΔcchA than in the parent or ΔcnaB strains, are likely to play important roles in response to salt stress. Furthermore, 36 genes were exclusively upregulated in the ΔcnaBΔcchA under salt stress. F...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Zuzana Hruska, Haibo Yao, Russell Kincaid, Robert L. Brown, Deepak Bhatnagar, Thomas E. Cleveland
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 205. Question 1 Meigs’ Syndrome resolves after removal of the tumour. What is the classic triad of Meigs’ Syndrome? + Reveal the Funtabulous Answer expand(document.getElementById('ddet771338363'));expand(document.getElementById('ddetli...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Frivolous Friday Five allergic bronchopulmonary aspergillosis Argyll Robertson aspergilloma aspergillus Calabar extrinsic allergic alveolitis invasive aspergillosis kartagener's syndrome liver Loa loa worms Meigs syndrome ocular oa Source Type: blogs
Conclusion La prévalence de la résistance est élevée chez les patients atteints de mucoviscidose mais encore faible dans la population à risque d’AI. Avec une sensibilité supérieure à celle de la culture, MycoGENIE® apporte un bénéfice pour le diagnostic d’AI. Cependant, la détection de résistance est limitée à une seule mutation, et sa sensibilité restreinte du fait de la présence d’une copie unique du cyp51A par génome d’Aspergillus. Avec la limite du nombre restreint d’...
Source: Journal of Medical Mycology - Category: Biology Source Type: research
Conclusions Les isolats d’A. fumigatus environnementaux et cliniques retrouvés au sein de notre établissement hospitalier ne présentent pas de résistance aux azolés. Cependant, face au risque accru pour les patients d’être infectés par une souche d’emblée résistante aux azolés, il paraît intéressant d’effectuer un suivi régulier de l’écologie environnementale des souches d’A. fumigatus.
Source: Journal of Medical Mycology - Category: Biology Source Type: research
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