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Oxidative stressors modify the response of Streptococcus mutans to its competence signal peptides.

In this study we used fluorescent reporters to probe the effect of reactive oxygen species on competence signaling at the single cell level. Our data show that different reactive oxygen species have different effects on S. mutans competence, and that some portions of the signaling pathway are more acutely sensitive to oxidative stress than others. PMID: 28887419 [PubMed - as supplied by publisher]
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research

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In conclusion, although the presence of moderate and extensive lesions at baseline is a significant predictor for cavitated caries increment after 2 years in preschool children at all ages, the presence of only initial caries lesions is also associated, but with less severe caries incidence.Caries Res 2018;52:32-41
Source: Caries Research - Category: Dentistry Source Type: research
CONCLUSION: Dental caries was not associated with BMI but age significantly influenced the DMFT index and gender was associated with more missing teeth. Further longitudinal studies with larger cohorts from several geographic regions are warranted. LIMITATION:Convenience sampling and recruitment from a single dental center may have some impact on the generalization of data.   
Source: Annals of Saudi Medicine - Category: General Medicine Tags: ISSUE 6 Source Type: research
Authors: Ladewig NM, Camargo LB, Tedesco TK, Floriano I, Gimenez T, Imparato JCP, Mendes FM, Braga MM, Raggio DP Abstract INTRODUCTION: Dental caries is the most prevalent non-communicative disease worldwide. Although the etiological factors are well known for years, reducing the number of decayed and missing teeth in children still remains as a barrier. Preventive and curative options are numerous but little is known about their economical advantages. Selecting the intervention that offers the best balance of effectiveness and financial resources becomes crucial in the current situation of budget restrictions worl...
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
The objective of this preliminary study was to verify if there is agreement between objective and subjective validated methods of chewing evaluation in a convenience sample which consisted of 32 adolescents (mean 15.5years), complete permanent dentition and free of tooth decay. The Quality of Masticatory Function Questionnaire with the Food-Mastication, Habits, Meat, Fruit and Vegetables domains was used in the subjective evaluation. The objective aspects consisted of maximum bite force (BF) and masticatory performance (MP) by mastication of cubes of test-material and sieving to determine the median particle size (X50) and...
Source: Physiology and Behavior - Category: Physiology Source Type: research
Conclusions: In vitro microbiological tests demonstrate that the hydroalcoholic extracts of pomegranate juice and peel are able to contrast the main cariogenic bacteria involved in tooth decay. Although being preliminary data, our results suggest that pomegranate polyphenolic compounds could represent a good adjuvant for the prevention and treatment of dental caries. PMID: 29209624 [PubMed - in process]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Authors: Khadem Nezhad S, Taghavi Zenouz A, Aghazadeh M, Samadi Kafil H Abstract Lactobacillus spp. are one of the first microorganisms involved in the development of dental caries in the first years of life of the child. The purpose of this study was to investigate the antibacterial effect of alcoholic extract of hypericin against strains of Lactobacillus spp. and determine its related MIC (minimum inhibitory concentration); and cytotoxic effect against gingival fibroblasts. Antimicrobial activity and MIC were evaluated using micro broth dilution method based on CLSI (clinical and laboratory standards institute) p...
Source: Cellular and Molecular Biology - Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research
Aim: Assessment of dental health in the primary dentition of preterm infants (PTI) including investigation of mother- and infant-related risk factors in a case-control study design.Material and Methods: One hundred twenty-eight infants aged 3-4 years were included. Sixty-four PTI (27 males) were randomly selected from the preterm registry of the Jena University Hospital. As a control group served 64 full-term infants (FTI) recruited from the Department of Paediatric Dentistry, matched for age and sex. Dental examinations were provided by one dentist under standard clinical conditions. Caries was scored using the Internatio...
Source: Caries Research - Category: Dentistry Source Type: research
We report on a morbidly obese 16-year-old boy (weight, 116 kg; height, 176 cm; body mass index, 35.5 kg/m2) with mitochondrial encephalomyopathy and a history of cerebral infarction, epilepsy, and severe mental retardation. The patient was scheduled for elective surgery under general anesthesia for multiple dental caries and entropion of the left eye. Preoperative examination results, including an electrocardiogram, were normal. No obvious cardiac function abnormalities were observed on echocardiography. Midazolam (10 mg) was administered orally as premedication 30 minutes before transfer to the operating room; however, th...
Source: Anesthesia Progress - Category: Anesthesiology Tags: Anesth Prog Source Type: research
Researchers at the University of Pennsylvania have developed an antibacterial resin for dental procedures such as cavity fillings. They hope that the material can provide improved fillings that resist tooth decay and last longer. Conventional materials for dental fillings are prone to being covered in plaque, a sticky biofilm that can lead to tooth decay and filling failure. Researchers at the University of Pennsylvania are working on developing something better. “Dental biomaterials such as these,” said Geelsu Hwang, a researcher involved in the study, “need to achieve two goals: first, they should kill ...
Source: Medgadget - Category: Medical Devices Authors: Tags: Dentistry Materials Source Type: blogs
(Natural News) While most parents are often worried about their kids getting injured while playing outdoors, a whopping 35,000 children younger than 10 needed tooth decay treatment in 2016 and 2017. According to statistics, children under 10 are now twice as likely to be hospitalized due to tooth decay rather than a broken arm. The worrisome...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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