Red cell alloimmunization in repeatedly transfused patients

Conclusions: Alloantibodies should be identified in repeatedly transfused patients and should be given corresponding antigen negative blood unit which will minimize the antibody mediated destruction of transfused red cells.
Source: Asian Journal of Transfusion Science - Category: Hematology Authors: Source Type: research

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VITAMIN B12 deficiency can result in anaemia, but among its symptoms are headaches and a reduced appetite. The vitamin is vital in keeping the body in the best condition, but because the body doesn ’t make the vitamin it’s important to get it from a balanced diet. Here are six foods that are all good sources of B12.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Millbourn C, Psaros Einberg A, Lindh G, Hökeberg I, Fischler B, Lindahl K Abstract OBJECTIVES: The prevalence of hepatitis C virus (HCV) infection in Sweden is estimated to 0.5%. Before 1992, blood transfusion posed a risk of HCV transmission. The primary aim of this study was to estimate anti-HCV prevalence in Stockholm County among individuals receiving blood transfusions 1965-1991. The secondary aim was to study the effect of age at transfusion on the development of liver disease and treatment outcome. MATERIALS AND METHODS: This is a retrospective analysis of individuals found to be anti-HCV t...
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Conditions:   Postoperative Anemia;   Knee Osteoarthritis;   Total Knee Arthroplasty Interventions:   Drug: Ferric carboxymaltose;   Drug: 0.9% Normal Saline Sponsor:   The Catholic University of Korea Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Postoperative Anemia;   Knee Osteoarthritis;   Total Knee Arthroplasty Interventions:   Drug: Ferric carboxymaltose;   Drug: 0.9% Normal Saline Sponsor:   The Catholic University of Korea Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Iron Deficiency Anemia Intervention:   Dietary Supplement: Ferrous Sulfate Sponsor:   Icahn School of Medicine at Mount Sinai Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: Wandering spleen should ideally be treated on an elective or semi-elective basis. Surgical delays could be partially minimized by a high index of suspicion at diagnosis and by eliminating unnecessary and time-consuming repeated imaging studies. PMID: 29911755 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
This year brings a bit of good news regarding the drug pipeline for sickle cell disease, but pain management is a growing problem.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
Publication date: Available online 18 June 2018 Source:Best Practice & Research Clinical Endocrinology & Metabolism Author(s): Jens Bollerslev, Mikkel Pretorius, Ansgar Heck Parathyroid independent hypercalcemia is characterized by suppressed parathyroid hormone (PTH) in the presence of hypercalcemia. Well known causes and mechanisms are redistribution of calcium from the skeleton, by malignant diseases; inadequately increased intestinal calcium uptake mediated by increased vitamin D activity, and reduced renal elimination due to medications. Frequent and infrequent causes are discussed, and more recent mechanisti...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Publication date: August 2018 Source:Journal of Critical Care, Volume 46 Author(s): Dilip R. Karnad, Guy A. Richards, Gisele Sampaio Silva, Pravin Amin Tropical infections form 20–30% of ICU admissions in tropical countries. Diarrheal diseases, malaria, dengue, typhoid, rickettsial diseases and leptospirosis are common causes of critical illness. Overlapping clinical features makes initial diagnosis challenging. A systematic approach involving (1) history of specific continent or country of travel, (2) exposure to specific environments (forests or farms, water sports, consumption of exotic foods), (3) incubation per...
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
ConclusionBecause of the importance of folate in one-carbon metabolism, the potential influence of vitamin C intake on the time taken to deplete the liver folate store should be experimentally investigated.
Source: BMC Hematology - Category: Hematology Source Type: research
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