What Proteins Cause Cow ’ s Milk Protein Allergy?
Discussion Cow’s milk protein allergy (CMPA) is one of the most common food allergies. It is estimated to have an incidence of 2-7.5% in infants and a prevalence of 0.5% in breastfeed infants. The prevalence decreases with age at 1% in children> or = 6 years. CMPA does not have a laboratory test and therefore is a clinical diagnosis. It is defined as a “hypersensitivity reaction brought on by specific immunologic mechanisms to cow’s milk.” Generally symptoms present within the first month of life and involve 2 of more systems with 2 or more symptoms. Systems are dermatologic (including atopic dermatitis, urticaria, oral pruritis), respiratory (including asthma, stridor, wheezing, rhinoconjunctivitis) and gastrointestinal (including emesis, diarrhea, constipation, malabsorption, gastroestophageal reflux disease) and other symptoms may include colic, irritability, failure to thrive or food aversion. IgE-mediated CMPA (Type 1 hypersensitivity reaction, ~50% of children) has symptoms that occur within minutes to 2 hours of ingestion of the CMP. Non-IgE mediated CMPA (Type 4 delayed hypersensitivity reaction) has symptoms that occur 4 or more hours (even up to 1 week) after exposure to CMP. Allergic colitis can have blood mixed into stools that are usually non-foul smelling, mucousy or foamy. Blood can be hematochezia or melanotic or insidious. The mechanism for rectal bleeding is felt to be ulceration of thinned mucosa that is stretched over enlarged h...
We describe a case where this pathology is observed associated with bone lithic lesions and kidney failure and it was diagnosed with transbronchial cryobiopsy. PMID: 32945642 [PubMed - as supplied by publisher]
Invasive breast cancer deriving from the milk duct and lobule that develops in the nipple is extremely rare, except in Paget ’s disease and skin cancer. This is the second reported case of the development of invasive cancer confined to the nipple after breast-conserving surgery. A 69-year-old woman visited our department due to redness, swelling, and bloody discharge of the right nipple in the last month. A needle biops y was suggestive of invasive ductal carcinoma; we performed a removal surgery of the right residual breast tissue and a second sentinel lymph node biopsy. She underwent these procedures 10 years previ...
A better understanding of the role of the intestinal microbiota in the development of chronic health issues in children could have important implications for prevention and treatment.Pediatric Nursing
Severe peanut allergies in children jump 85 per cent on Halloween and 60 per cent on Easter, and other nut allergies follow the same trend, possibly due to social gatherings where sweets are shared
Publication date: December 2020Source: LWT, Volume 134Author(s): Xinyan Yang, Xiaojie Guo, Weipeng Liu, Yazhen Tian, Pingping Gao, Yuwei Ren, Wei Zhang, Yujun Jiang, Chaoxin Man
CONCLUSION: Our results showed that the evaluation of the disease process from 3 days to nine days after a 10 min contact of acid to the colon is a suitable model that mimics the histological features of the disease. PMID: 32945217 [PubMed - as supplied by publisher]
Authors: Hatipoğlu Ö, Hatipoglu FP Abstract Objectives: This meta-analysis aimed to examine the comprehensive conclusive evidence of association between asthma and caries-related salivary factors including salivary pH (SpH), salivary flow rate (SFR), salivary buffer capacity (SBC), and other salivary components.Methods: Electronic databases (Web of Science, PubMed, Scopus, Cochrane Library, and Open Grey databases) were searched for relevant studies. After screening, studies were selected and data were collected from each study. The risk of bias in individual studies and across studies was evaluated. Mean dif...
Authors: Agrawal S, Iqbal S, Patel SJ, Freishtat R, Kochhar-Bryant C Abstract IntroductionAsthma is the most common chronic condition of childhood. Urban, minority children from families of lower socioeconomic status have disproportionately higher rates of asthma and worse outcomes. We investigated the association between the presence of asthma and asthma severity among American, urban, minority children and reported quality of life (QOL) of children and their families.MethodsWe performed a prospective, cross-sectional study comparing QOL of urban, minority children in elementary school-age with and without asthma....
Authors: Alberca RW PMID: 32942904 [PubMed - as supplied by publisher]
Authors: Zhao CY, Consuegra-Romero G PMID: 32946593 [PubMed - as supplied by publisher]
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