What Proteins Cause Cow ’ s Milk Protein Allergy?

Discussion Cow’s milk protein allergy (CMPA) is one of the most common food allergies. It is estimated to have an incidence of 2-7.5% in infants and a prevalence of 0.5% in breastfeed infants. The prevalence decreases with age at 1% in children> or = 6 years. CMPA does not have a laboratory test and therefore is a clinical diagnosis. It is defined as a “hypersensitivity reaction brought on by specific immunologic mechanisms to cow’s milk.” Generally symptoms present within the first month of life and involve 2 of more systems with 2 or more symptoms. Systems are dermatologic (including atopic dermatitis, urticaria, oral pruritis), respiratory (including asthma, stridor, wheezing, rhinoconjunctivitis) and gastrointestinal (including emesis, diarrhea, constipation, malabsorption, gastroestophageal reflux disease) and other symptoms may include colic, irritability, failure to thrive or food aversion. IgE-mediated CMPA (Type 1 hypersensitivity reaction, ~50% of children) has symptoms that occur within minutes to 2 hours of ingestion of the CMP. Non-IgE mediated CMPA (Type 4 delayed hypersensitivity reaction) has symptoms that occur 4 or more hours (even up to 1 week) after exposure to CMP. Allergic colitis can have blood mixed into stools that are usually non-foul smelling, mucousy or foamy. Blood can be hematochezia or melanotic or insidious. The mechanism for rectal bleeding is felt to be ulceration of thinned mucosa that is stretched over enlarged h...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

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We describe a case where this pathology is observed associated with bone lithic lesions and kidney failure and it was diagnosed with transbronchial cryobiopsy. PMID: 32945642 [PubMed - as supplied by publisher]
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
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Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
A better understanding of the role of the intestinal microbiota in the development of chronic health issues in children could have important implications for prevention and treatment.Pediatric Nursing
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pediatrics Journal Article Source Type: news
Severe peanut allergies in children jump 85 per cent on Halloween and 60 per cent on Easter, and other nut allergies follow the same trend, possibly due to social gatherings where sweets are shared
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Publication date: December 2020Source: LWT, Volume 134Author(s): Xinyan Yang, Xiaojie Guo, Weipeng Liu, Yazhen Tian, Pingping Gao, Yuwei Ren, Wei Zhang, Yujun Jiang, Chaoxin Man
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CONCLUSION: Our results showed that the evaluation of the disease process from 3 days to nine days after a 10 min contact of acid to the colon is a suitable model that mimics the histological features of the disease. PMID: 32945217 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
Authors: Hatipo─člu Ö, Hatipoglu FP Abstract Objectives: This meta-analysis aimed to examine the comprehensive conclusive evidence of association between asthma and caries-related salivary factors including salivary pH (SpH), salivary flow rate (SFR), salivary buffer capacity (SBC), and other salivary components.Methods: Electronic databases (Web of Science, PubMed, Scopus, Cochrane Library, and Open Grey databases) were searched for relevant studies. After screening, studies were selected and data were collected from each study. The risk of bias in individual studies and across studies was evaluated. Mean dif...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
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Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: Alberca RW PMID: 32942904 [PubMed - as supplied by publisher]
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Authors: Zhao CY, Consuegra-Romero G PMID: 32946593 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
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