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Nurses' regular use of disinfectants is associated with developing COPD

(European Lung Foundation) Regular use of disinfectants is linked to a higher risk of developing chronic obstructive pulmonary disease (COPD), according to new research looking at incidence of the disease in over 55,000 nurses in the USA, to be presented at the European Respiratory Society International Congress.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Authors: Anderson LJ, Liu H, Garcia JM Abstract With aging and other muscle wasting diseases, men and women undergo similar pathological changes in skeletal muscle: increased inflammation, enhanced oxidative stress, mitochondrial dysfunction, satellite cell senescence, elevated apoptosis and proteasome activity, and suppressed protein synthesis and myocyte regeneration. Decreased food intake and physical activity also indirectly contribute to muscle wasting. Sex hormones also play important roles in maintaining skeletal muscle homeostasis. Testosterone is a potent anabolic factor promoting muscle protein synthesis ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Condition:   Physiology Interventions:   Device: Anodal transcranial direct-current-stimulation;   Device: Sham transcranial direct-current-stimulation Sponsor:   5 Santé Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: NCDs and their risk factors are emerging problems in Vietnam, which need both disease-specific and sensitive strategies in health and related sectors. PMID: 29222878 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Asia Pac J Clin Nutr Source Type: research
ABSTRACT Background and objectiveNon‐invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model of care remains unknown. MethodsWe conducted a prospective observational non‐inferiority study comparing three models of NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant ward round), a high dependency unit (HDU) (1:2 ratio, twice daily ward round) and an intensive care unit (ICU) (1:1 ratio, twice daily ward round) model in three similar teaching tertiary hospitals. Changes in arterial blood gases (ABG) and clinical outco...
Source: Respirology - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
This study assessed the cost-effectiveness of indacaterol/glycopyrronium (IND/GLY) versus salmeterol/fluticasone (SFC) in chronic obstructive pulmonary disease (COPD) patients with moderate to very severe airf...
Source: Respiratory Research - Category: Respiratory Medicine Authors: Tags: Research Source Type: research
ABSTRACT Purpose: To assess the incidence of pulmonary thromboembolism (PTE) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), and to evaluate the efficacy and safety of low‐dose urokinase (UK) thrombolysis therapy when treating hemodynamically stable AECOPD patients with acute PTE (AECOPD‐PTE). Methods: A total of 419 AECOPD patients, including 96 AECOPD‐PTE, were enrolled. 30 AECOPD‐PTE patients were collected retrospectively and 66 AECOPD‐PTE patients were prospectively divided into anticoagulation‐only, low‐dose UK and standard‐dose UK groups. Follow‐up one year, w...
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
ABSTRACT Background: Blood biomarkers are easily accessible and might reflect chronic obstructive pulmonary disease (COPD) activity. Aim: To determine whether a panel of blood biomarkers (C‐reactive protein [CRP], neutrophils, eosinophils, albumin and vitamin D) could predict mortality in COPD. Methods: we analyzed data from 431 COPD participants to the 2007‐2010 National Health and Nutrition Examination Surveys who were followed for a median time of 36 months. COPD was defined as post‐bronchodilator forced expiratory volume in 1 second (FEV1) and forced vital capacity ratio
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
Publication date: Available online 9 December 2017 Source:Pulmonary Pharmacology & Therapeutics Author(s): Mario Cazzola, Luigino Calzetta, Clive Page, Paola Rogliani, Maria Gabriella Matera A previous meta-analysis suggested that the treatment with erdosteine was associated with significant amelioration of the cumulative global efficacy index and symptoms in comparison to placebo or other mucolytics. However, this conclusion was criticized because the meta-analysis, as it had been done, made it impossible to preclude the potential operation of selection biases within and across trials, and identify any realised benef...
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
Conclusions: The increased expression of TLR2 and TLR4 suggests its role in disease pathogenesis of COPD. Smoke pack years was negatively associated with spirometric parameters in COPD patients. This may help to predict the smokers without COPD who risk developing the condition in the future. PMID: 29218124 [PubMed]
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
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