Respiratory tract infections in young children linked to asthma and worse lung function
(European Lung Foundation) Respiratory tract infections in young children are linked to an increased risk of asthma and worse lung function in later life, according to new research to be presented at the European Respiratory Society International Congress. An international study of 154,942 European children found a 1.5- to four-fold increased risk.
CONCLUSIONS: Inhaled budesonide can down-regulate the expressions of LIGHT, LTβR, and HVEM in the lungs of asthmatic mice, and LIGHT/LTβR/HVEM interactions may be a potentially key target for asthma treatment. PMID: 29140131 [PubMed - in process]
Propeller Health said today it inked a strategic partnership deal with Express Scripts (NSDQ:ESRX) to provide Propeller’s digital solutions to Express Script members. Through the deal, St. Louis-based Express Script members will be able to use inhaler sensors and connected mobile applications to manage their asthma or chronic obstructive pulmonary disease. The companies touted it as the largest respiratory digital health deployment with a pharmacy manager to date. Read the whole story on our sister site, Drug Delivery Business The post Propeller Health, Express Scripts ink smart inhaler sensor deal app...
-- Smoke from a nearby wildfire threatens anyone, but poses even more of a threat to people with asthma, COPD, heart disease or diabetes, the American Lung Association says. The group suggests what to do if a wildfire burns near you: Stay inside,...
In conclusion, air pollution was associated with dispensed asthma medications, especially in areas with comparatively higher levels of air pollution, and in children to parents with high education. We did not observe support for our hypothesis that stressors linked to socio-economy or mental health problems would increase susceptibility to the effects of air pollution on the development of asthma.
Conclusions These findings could help inform the evaluation of interventions to prevent and manage noncommunicable chronic diseases and their potential to control costs among the vulnerable Medicaid population.
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ConclusionCases with RV‐ and RSV‐induced early‐childhood wheezing had increased risk for asthma in adulthood, and RV‐positive cases had significantly higher FENO values than RSV‐positive cases and controls. Compared to controls RV‐positive cases showed more bronchial reactivity, and RSV‐positive cases showed lower FVC before bronchodilation in lung function testing. Clinical relevanceChildren with RV‐ or RSV‐induced wheezing in early childhood have an increased risk for asthma and lung function abnormalities in adulthood.This article is protected by copyright. All rights reserved.
Study found fracture risk is not significantly increased with daily inhaled steroids in children with asthma compared with no steroid use; the authors encourage use when indicated.Medscape Medical News
Benralizumab, an interleukin-5 receptor inhibitor, targets and rapidly depletes eosinophils and is the first respiratory biologic with an 8-week maintenance dosing schedule.FDA Approvals
Conclusion Multifunctional mHealth apps have good potential in the control of asthma and in improving the quality of life in such patients compared with traditional interventions. Further studies are needed to identify the effectiveness of these interventions on outcomes related to medication adherence and costs....