Fluctuation of zonulin levels in blood vs stability of antibodies.

CONCLUSION: Due to its fluctuation, a single measurement of zonulin level is not recommended for assessment of intestinal barrier integrity. Measurement of IgG and IgA antibodies against zonulin, occludin, and other tight junction proteins is proposed for the evaluation of the loss of intestinal barrier integrity.
PMID: 28883692 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - August 21, 2017 Category: Gastroenterology Authors: Vojdani A, Vojdani E, Kharrazian D Tags: World J Gastroenterol Source Type: research