Resistant hypertension: an overview.

Resistant hypertension: an overview. Minerva Cardioangiol. 2017 Sep 05;: Authors: Pedrinelli R, Dell' Omo G, Ambrosio G, Cameli M, Cerbai E, Coiro S, Emdin M, Liga R, Marcucci R, Morrone D, Palazzuoli A, Padeletti L, Savino K, Società Italiana di Cardiologia, Sezione Regionale Tosco-Umbra Abstract Despite the availability of anti-hypertensive medications with proven efficacy and good tolerability, many hypertensive patients have blood pressure levels(BP) not at the goals set by international societies. Some of these patients are either non-adherent to the prescribed drugs or not optimally treated. However, a proportion, despite adequate treatment, has resistant hypertension(RH) defined as office BP above goal despite the use of ≥3 antihypertensive medications at maximally tolerated doses (one ideally being a diuretic). Diagnosis of RH based upon office measurements, however, needs confirmation through 24-h BP monitoring to exclude "white coat" RH since cardiovascular events and mortality rates follow mean ambulatory BPs. Although several studies have approached the issue of the prevalence of RH in the hypertensive population, its prevalence is by and large based upon reasonable but approximate estimates for reasons detailed in the text. Standardized combination therapy based upon angiotensin converting enzyme inhibitors or angiotensin receptor blockers, amlodipine or other dihydropiridine calcium channel blockers and a diuretic (thiazi...
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

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This report provides 2017-2018 U.S. hypertension prevalence estimates using the 2017 American College of Cardiology and American Heart Association definition of hypertension (3) and new guidelines, which redefine hypertension by lowering the previous threshold levels of 140/90 mmHg to 130/80 mmHg (4). This change categorizes a greater percentage of people as having hypertension. PMID: 32487290 [PubMed - in process]
Source: NCHS data brief - Category: American Health Tags: NCHS Data Brief Source Type: research
Conclusion ACE I/D polymorphism may protect against the development of PE. PMID: 32484368 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Conditions:   HIV/AIDS;   Noncommunicable Diseases;   Hypertension;   Diabetes Interventions:   Other: Integrated Community-Based Care;   Other: Microfinance with Standard of Care Sponsors:   Brown University;   Johns Hopkins University;   Moi University;   Purdue University;   University of Toronto;   NYU Langone Health;   Academic Model Providing Access to Healthcare (AMPATH);   National Institute of Mental Health (NIMH) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Pulmonary Arterial Hypertension Intervention:   Drug: Imatinib Mesylate Sponsors:   Imperial College London;   National Institute for Health Research, United Kingdom;   Medical Research Council;   University of Cambridge;   University of Sheffield Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Hospitalists often care for patients with liver disease, including those with acute liver injury and failure and patients with complications of decompensated cirrhosis. Acute liver failure is a true emergency, requiring intensive care and oftentimes transfer of the patient to a liver transplant center. Patients with decompensated cirrhosis have complications of portal hypertension, including variceal hemorrhage, ascites, spontaneous bacterial peritonitis, and hepatic encephalopathy. These complications increase the risk of mortality among patients with decompensated cirrhosis. Comanagement by the hospitalist with gastroent...
Source: Medical Clinics of North America - Category: Primary Care Authors: Source Type: research
Publication date: Available online 3 June 2020Source: Neurología (English Edition)Author(s): I. Gonzalez-Marrero, L.G. Hernández-Abad, L. Castañeyra-Ruiz, E.M. Carmona-Calero, A. Castañeyra-Perdomo
Source: Neurologia - Category: Neurology Source Type: research
CONCLUSION: The design results revealed that an optimum exposure of 1:2 of isopropanol: formaldehyde vapours for sixty minutes resulted in desired release of second pulse of dose after a predetermined lag time of 5 hours as desired. '3Cap' system was successful in achieving floating and pulsed release of hypertensive drug opening a 'new lease of life' to the existing drug molecule. PMID: 32484113 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research
Resumo Revis ão sistemática sobre fatores demográficos, socioeconômicos, comportamentais e antropométricos associados à hipertensão (HAS). Foram incluídos estudos observacionais, de populações com 18 anos ou mais, dos últimos dez anos, publicados em inglês, português ou espanhol das bases Pubmed, We b of Science, Scopus e Lilacs. Ao final, foram incluídos 42 artigos, a maioria do tipo seccional. A idade e o Índice de Massa Corporal (IMC) elevados foram os fatores relacionados à maior chance de ter HAS mais encontrad...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
ConclusionRobotically assisted Heller myotomy and POEM are safe and efficacious treatments for achalasia with lower rates of technical complications compared to laparoscopic Heller myotomy. With the advancements in endoscopic instruments and robotic surgery, POEM and robotically assisted Heller myotomy should be considered in the treatment of achalasia and esophageal dysmotility disorders.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Conclusion: In patients with CS and PFO, the likelihood of prior stroke is associated with both, PFO-related and PFO-unrelated factors.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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