512 The Decrease of psoriatic redness by PEMF in IL 17A-treated Keratinocytes

Psoriasis is a long-lasting autoimmune disease. That consists of three parts, the first is abnormal keratinocyte differentiation, the second is hyperproliferation and the third is inflammatory elements influencing redness. Once pathogenic T cells have entered the skin, they become activated and release cytokines and chemokines to attract other immune cells to perpetuate the inflammatory cascade. Many kinds of chemokine “CXC” subfamily were expressed in psoriatic region. Keratinocytes play an important role in the regulation of skin immune response, responding to environmental stimuli.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Inflammation, Immunity and Infection Source Type: research