605 Strong FGF1 signaling inhibits the proliferation, invasion and migration of murine angiosarcoma cell line ISOS-1

This study aimed at clarifying the effect of FGF1 signaling on the malignancy of murine angiosarcoma cell line ISOS-1. Highly stable FGF1 mutants were developed previously to increase mitogenic activity more than wild-type FGF1, so ISOS-1 cells were cultured in complete DMEM medium with each FGF1 mutant to examine their effects in the proliferation, migration, and invasion of ISOS-1 cells.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Melanoma and Other Skin Cancers Source Type: research