Is it time for one-step nucleic acid amplification (OSNA) in colorectal cancer? A systematic review and meta-analysis

ConclusionsOSNA is as good as routine HE. It may avoid TAB and offer a more objective and standardised assay of LNM. However, for upstaging, its usefulness as an adjunct to HE or superiority to HE requires further assessment of the benefits, if any, of adjuvant therapy in patients upstaged by OSNA.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research