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Fully Funded PhD position: Pattern Recognition Receptors in Antimicrobial Immunity

Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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In conclusion, a dysbiotic mycobiome dominated by C. albicans was found in association with OSCC, a finding worth further investigation. PMID: 29152157 [PubMed]
Source: Journal of Oral Microbiology - Category: Microbiology Tags: J Oral Microbiol Source Type: research
Summary Fungal sensitisation in adults is associated with severe asthma but prevalence and clinical significance of fungal sensitisation remains unclear in paediatric population. The aim of this study was to study the association of fungal sensitisation with disease severity in children with persistent asthma. One hundred children with persistent asthma in age group 7‐15 years, symptom duration>2 years and forced expiratory volume in first second>50% of expected were enrolled. Skin prick test (SPT) to 8 fungal antigens and total serum immunoglobulin E (IgE) were done. Fungal sensitisation was described as...
Source: Mycoses - Category: Research Authors: Tags: ORIGINAL ARTICLE Source Type: research
The incidence of tuberculosis (TB) is high among human immunodeficiency virus (HIV) infected Ugandans. Recent evidence suggests that Chronic Pulmonary Aspergillosis and Aspergillus sensitisation might be responsi...
Source: BMC Pulmonary Medicine - Category: Respiratory Medicine Authors: Tags: Research article Source Type: research
Methyl (3-hydroxy-4-(2-hydroxy-6-methylheptan-2-yl)benzoyl)glycinate (1), a new sydonic acid derivative with glycinate, together with sydonic acid (2), sydowic acid (3), and 7-deoxy-7,14-didehydrosydonic acid (4), were isolated from a marine-derived Aspergillus sydowii strain CUGB-F126. Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1D and 2D NMR techniques. All of these compounds did not show inhibitory activity against Staphylococcus aureus and Candida albicans.
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
Publication date: April 2018 Source:Journal of Food Engineering, Volume 222 Author(s): Ehsan Jenab, Mehdi Omidghane, Paolo Mussone, Daniel Hernandez Armada, Jonathan Cartmell, Carlo Montemagno Galacto-oligosaccharides (GOS) synthesized from lactose using Aspergillus oryzae β-galactosidases. We studied the influences of enzyme concentration (0.02–0.1%. w/v), temperature (40–70 °C), pH (4.5–8), lactose concentration (5–40%, w/v) and foam architecture reaction media on formation of GOS. The total GOS increased from about 7 to 23 (wt.% of initial lactose) with an increase in lactose from ...
Source: Journal of Food Engineering - Category: Food Science Source Type: research
• Co-infection is frequent in influenza-related ARDS requiring ECMO support• Staphylococcus aureus is the most common pathogen• Panton–Valentin leukocidin-producing Staphylococcus aureus is frequent• Aspergillus fumigatus co-infection is frequent in influenza-associated severe pneumonia
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research
The objective of the current study is to investigate the hydrolysis of pectinaceous matter in guava juice and to model the depectinization kinetics using commercial pectinase from Aspergillus niger. The procedure involves enzymatic treatment of guava juice at 45 °C with enzyme concentration (% w/w) 0.033, 0.055, 0.078 and 0.1. The degree of hydrolysis of pectinaceous matter and the rate of enzymatic reaction are determined. The results show an increase in the degree of hydrolysis with time for each enzyme concentration. Depectinization kinetics reveal allosteric behavior and is modeled using the Hill Equation. The...
Source: Journal of Food Engineering - Category: Food Science Source Type: research
Guangshan Yao, Feng Zhang, Xinyi Nie, Xiuna Wang, Jun Yuan, Zhenhong Zhuang, Shihua Wang
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Chronic Pulmonary aspergillosis (CPA) is a well described spectrum of the disease caused by the fungi belonging to the Aspergillus species first described in 1842 as a complication of tuberculous cavities. Advances in thoracic surgery and advances of antifungal therapy in the late 1900s led to the first cure[1]. Aspergillosis is a disease process that varies based on the level of immunosupression; angioinvasive aspergillosis is present in a setting of profound immunosupression and allergic bronchopulmonary aspergillosis in a hyperimmune setting.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the Editor Source Type: research
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