Fully Funded PhD position: Pattern Recognition Receptors in Antimicrobial Immunity

Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Molecules, Vol. 23, Pages 1516: Microbial Hydrolysis of Racemic β-Aryl-γ-ethylidene-γ-lactones and Antifeedant Activity of the Products against Alphitobius diaperinus Panzer Molecules doi: 10.3390/molecules23071516 Authors: Andrzej Skrobiszewski Witold Gładkowski Marcelina Mazur Maryla Szczepanik Gabriela Maciejewska Czesław Wawrzeńczyk Hydrolysis of (±)-β-aryl-γ-ethylidene-γ-lactones by fungal strain Aspergillus ochraceus AM370 afforded (−)-(S)-γ-ethylidene-γ-lactones 2a–d and (+)-(R)-γ-ketoacids...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Authors: Ferdouse J, Miyagawa M, Hirano M, Kitajima Y, Inaba S, Kitagaki H Abstract At present, the quantitation of the mycelial weight of the industrially important non-pathogenic fungus Aspergillus oryzae, which is used for manufacturing koji, is performed by quantitating N-acetylglucosamine. However, since N-acetylglucosamine is a cell wall component, the extraction procedure is costly and tedious, and its quantitative performance is poor. Here, we report a novel method for the quantitation of A. oryzae mycelial weight. The amount of glycosylceramide significantly correlated with both the mycelial weight of A. o...
Source: Journal of General and Applied Microbiology - Category: Microbiology Tags: J Gen Appl Microbiol Source Type: research
Conclusion: A strong clinical suspicion that translates into early vitrectomy plus intravitreal antifungal antibiotics leads to favorable visual and structural outcomes. A long wait till microbiological confirmation to institute antifungal therapy may result in poorer outcome.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Fri, 06/22/2018 - 09:11News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Publication date: 1 December 2018 Source:Food Chemistry, Volume 268 Author(s): Qingyi Wei, Xiaomei Wang, Jun-Hu Cheng, Guangxiang Zeng, Da-Wen Sun A series of sorbic and benzoic acid amide derivatives were synthesized by conjugating sorbic acid (SAAD, a1 –a7 ) or benzoic acid (BAAD b1 – b6 ) with amino acid esters and their antimicrobial activities were investigated against Escherichia coli, Bacillus subtilis and Staphylococcus aureus, mixed bacteria from rancid milk, Saccharomyces cerevisiae, and Aspergillus niger. The antimicrobial activity of sorbic acid amides was better than that of benzoic acid amides. T...
Source: Food Chemistry - Category: Food Science Source Type: research
Thu, 06/21/2018 - 16:05News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Chitin is a polysaccharide that provides structure and rigidity to the cell walls of fungi and insects. Mammals possess multiple chitinases, which function to degrade chitin, thereby supporting a role for chitinases in immune defense. However, chitin degradation has been implicated in the pathogenesis of asthma. Here, we determined the impact of acidic mammalian chitinase (AMCase) (Chia) deficiency on host defense during acute exposure to the fungal pathogen Aspergillus fumigatus as well as its contribution to A. fumigatus-associated allergic asthma. We demonstrate that chitin in the fungal cell wall was detected at low le...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Host Response and Inflammation Source Type: research
Publication date: October 2018 Source:Phytochemistry Letters, Volume 27 Author(s): Madira Coutlyne Manganyi, Thierry Regnier, Ajay Kumar, Carlos Cornelius Bezuidenhout, Collins Njie Ateba Throughout history, mankind has used plants as their primary source of sustainability, in agricultural commodities, clothing, fragrances, fertilizers, flavours, and providing shelter. There is a strong symbiotic relationship between the plant and its endophytes. Endophytes are harboured within the living plant tissues without causing neither diseases nor symptoms. They produce bioactive compounds that protect the host plants against atta...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.
Source: ScienceNOW - Category: Science Authors: Tags: Immunology, Microbiology t-comment Source Type: news
Aouacheria et al. question the interpretation of contemporary assays to monitor programmed cell death with apoptosis-like features (A-PCD) in Aspergillus fumigatus. Although our study focuses on fungal A-PCD for host immune surveillance and infectious outcomes, the experimental approach incorporates multiple independent A-PCD markers and genetic manipulations based on fungal rather than mammalian orthologs to circumvent the limitations associated with any single approach.
Source: ScienceNOW - Category: Science Authors: Tags: Immunology, Microbiology t-comment Source Type: news
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