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Broncus Medical affiliate acquires Uptake Medical

Uptake Medical said yesterday that its InterVapor device for treating emphysema is back on the market in Europe after its acquisition for an undisclosed amount by an affiliate of Broncus Medical. Broncus set its purchase up under a new entity based in Seattle, Uptake Medical Technology, and plans to add markets in Australia and Asia to its commercial footprint in Europe by the end of the year. The InterVapor device uses heated water vapor to reduce lung volume in emphysema patients. Uptake won an expanded CE Mark in the European Union for InterVapor in August 2015. “2018 promises to be an exciting year for the new Uptake Medical,” founder &president Robert Barry said in prepared remarks. “With the recent outstanding Step-up multi-center randomized controlled trial results and the backing of Broncus, we are posed for success. In addition, we have very exciting bronchoscopic lung cancer ablation clinical studies underway. When you combine San Jose, Calif.-based Broncus Medical’s Archimedes system for accessing and diagnosing lung disease with [bronchial thermal vapor ablation] you start to see our vision of a complete interventional pulmonology company come to life.” “We also have plans to continue our research of BTVA for emphysema patients and expand the scope of patients that qualify. We are also continuing clinical research and development of our adaptation of the technology for the ablation of several other lung diseases,&r...
Source: Mass Device - Category: Medical Devices Authors: Tags: Mergers & Acquisitions Respiratory Wall Street Beat Broncus Medical Uptake Medical Source Type: news

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Abstract Lung cancer and chronic obstructive pulmonary disease (COPD) are leading causes of morbidity and mortality worldwide, and cigarette smoking is a main risk factor for both. The presence of emphysema, an irreversible lung disease, further raises the risk of lung cancer in COPD patients. The mechanisms involved in smoke-induced tumorigenesis and emphysema are not fully understood, attributable to a lack of appropriate animal models. Here, we optimized a model of cigarette smoke (CS)-induced lung cancer and emphysema in A/J mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a potent carci...
Source: American Journal of Respiratory Cell and Molecular Biology - Category: Molecular Biology Authors: Tags: Am J Respir Cell Mol Biol Source Type: research
AbstractThe purpose of this study was to clarify the clinicopathologic characteristics of non-small cell lung cancer (NSCLC) patients with combined pulmonary fibrosis and emphysema (CPFE). We investigated the association between CPFE, the cancer survival, and the pathological features of clinical stage I NSCLC patients. Between 2005 and 2014, 218 consecutive patients with clinical stage I NSCLC underwent complete resection with systematic lymph node dissection. A univariate analysis by log-rank tests was performed to determine the risk factors for recurrence, and the Cox proportional hazards regression model was used to id...
Source: Medical Oncology - Category: Cancer & Oncology Source Type: research
Purpose of review Chronic obstructive pulmonary disease (COPD) is a well established risk factor for lung cancer. Newer studies reveal a myriad of other mechanisms, some proven and some putative, which may contribute to their association. Recent findings There is an ever-growing bundle of evidence that suggests a close association between persistent chronic inflammation and lung cancer. A few potential targets of genetic susceptibility locus for COPD and lung cancer have been suggested. Better characterization of immune dysregulation and identification of signaling pathways may assist the development of strategies to ...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: OBSTRUCTIVE, OCCUPATIONAL AND ENVIRONMENTAL DISEASES: Edited by Manish Joshi and Basil Varkey Source Type: research
Conclusion Initial LDCT lung cancer screening at our institution yielded results similar to those of the National Lung Screening Trial. Thorough prescreening evaluation, joint decision-making, centralized coordination of screening-related care, and patient size conscious scanning protocols are critical elements of a safe and successful lung cancer screening program.
Source: Academic Radiology - Category: Radiology Source Type: research
Background: The purpose of this study was to assess the rate, cause, and factors associated with readmissions following pulmonary resection for lung cancer and their relationship with 90‐day mortality.Methods: A prospective cohort study was conducted of 379 patients who underwent surgery for lung cancer at the university hospitals Granada, Spain between 2012 and 2016.Results: The rate of readmissions within 30 postoperative days was 6.2%. The most common reason for readmission was subcutaneous emphysema (21.7%), pneumonia (13%), and pleural empyema (8.5%). A higher probability of requiring urgent readmission was associat...
Source: Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: RESEARCH ARTICLE Source Type: research
CT scans show that a quarter of the adult population has nonstandard airway...Read more on AuntMinnie.comRelated Reading: AI algorithm predicts lung disease, adverse events on CT COPD severity mirrors lung cancer incidence AJR: Ultralow-dose CT can evaluate COPD Group issues call for best lung cancer, COPD protocols Emphysema-related COPD on CT signals higher malignancy risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
By HUGH HARVEY, MD Artificial intelligence requires data. Ideally that data should be clean, trustworthy and above all, accurate. Unfortunately, medical data is far from it. In fact medical data is sometimes so far removed from being clean, it’s positively dirty. Consider the simple chest X-ray, the good old-fashioned posterior-anterior radiograph of the thorax. One of the longest standing radiological techniques in the medical diagnostic armoury, performed across the world by the billions. So many in fact, that radiologists struggle to keep up with the sheer volume, and sometimes forget to read the odd 23,000 of the...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized AI Data Hugh Harvey Radiology Source Type: blogs
ConclusionsThe GGA area on HRCT is a risk factor for chemotherapy-related AE-ILD. Therefore, this parameter can be used to predict the risk of AE-ILD before administering chemotherapy.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
Conclusion It is safe and feasible to apply digi tal drainage system to patients with postoperative refractory prolonged air leaks after pulmonary resection. Compared with the conventional drainage system, digital drainage system is more accurate and objective which can offer a larger suction pressure and promote lung recruitment maneuver for pleu rodesis, shortening the drainage time and length of hospital stay. DOI: 10.3779/j.issn.1009-3419.2017.12.07
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
Background: COPD patients have an increased risk of development of lung cancer, but its underlying mechanisms are poorly understood. We aimed to identify risk factors for lung cancer in patients from the Bergen COPD Cohort Study.Methods: We compared 433 COPD patients with 279 healthy controls, all former or current smokers. All COPD patients had a FEV1
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
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