Source: Leukemia Research - Category: Hematology Authors: Seon Young Kim, Kwantae Kim, Byungjin Hwang, Kyongok Im, Si Nae Park, Jung-Ah Kim, Sang Mee Hwang, Duhee Bang, Dong Soon LeeTags: Original Article Source Type: research
Conclusion.Azacitidine effects in these patients, most with non‐del(5q) LR‐MDS, were promising and generally similar to those reported for lenalidomide in similar patients. The choice of initial therapy is important because most patients eventually stop responding to front‐line therapy and alternatives are limited.Implications for Practice.Lower‐risk myelodysplastic syndromes (LR‐MDS) are primarily characterized by anemia. After erythropoiesis‐stimulating agent (ESA) failure, lenalidomide and hypomethylating agents are the only remaining treatment options for most patients. This meta‐analysis of 233 azacitidi...
Source: The Oncologist - Category: Cancer & Oncology Authors: Rami Komrokji, Arlene S. Swern, David Grinblatt, Roger M. Lyons, Magnus Tobiasson, Lewis R. Silverman, Hamid Sayar, Ravi Vij, Albert Fliss, Nora Tu, Mary M. SugrueTags: Leukemias, Academia-Pharma Intersect, Hematologic Malignancies ‐ Pharma Intersect: Hematologic Malignancies Source Type: research
Secondary Philadelphia chromosome acquired during therapy of acute leukemia and myelodysplastic syndrome, Published online: 14 February 2018; doi:10.1038/s41379-018-0014-xSecondary Philadelphia chromosome acquired during therapy of acute leukemia and myelodysplastic syndrome
Source: Modern Pathology - Category: Pathology Authors: Habibe Kurt Lan Zheng Hagop M. Kantarjian Guilin Tang Farhad Ravandi-Kashani Guillermo Garcia-Manero Zimu Gong Hesham M. Amin Sergej N. Konoplev Mark J. Routbort Xin Han Wei Wang L. Jeffery Medeiros Shimin HuSource Type: research
Conclusions: Patients with intestinal BD demonstrated a higher risk of hematologic cancer, especially leukemia, than the general population. Furthermore, women with intestinal BD showed a higher risk of all cancers.
PMID: 29429154 [PubMed - as supplied by publisher]
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
We report the extraordinary case of a patient with MDS who developed T‐LGLL, and subsequently the MDS progressed to CMML. The patient then developed diffuse arthropod bite‐like papules and intractable pruritus.
Source: Clinical And Experimental Dermatology - Category: Dermatology Authors: D. J. Lewis, R. N. Miranda, C. W. Oh, T. Hinojosa, L. J. Medeiros, J. L. Curry, M. T. Tetzlaff, C. A. Torres ‐Cabala, P. Nagarajan, F. Ravandi‐Kashani, M. DuvicTags: Concise Report Source Type: research