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Endoscopic Endo-Nasal Trans-Sphenoidal Excision of Pituitary Tumors: An Institutional Experience

AbstractTo analyze the clinical presentation, management and outcomes of patients with pituitary adenoma treated by Endoscopic Endo-nasal Trans-sphenoidal (EETS) excision. Study was conducted on the basis of medical records of 14 patients who had undergone EETS excision of pituitary adenomas. The data obtained was assessed for demographic and clinical characteristics, radiographic features and post-operative outcomes. Study included 10 males and 4 females. Mean age of patients was 46.43  years (range 16–70 Years). Most common presentation was diminished vision reported in 79% patients. Features of acromegaly encountered in 21% cases. Location of majority of tumors was sellar with supra-sellar extension (71%) followed by sellar (14%), sellar with para-sellar extension (7%) and se llar with supra-sellar and para-sellar extensions (7%). Total tumor resection was achieved in 64% cases and sub-total resection in 36% cases. One of the lesions on biopsy revealed granulomatous pathology. No post-operative complication was seen in 71% patients. Transient Diabetes Insipidus was obser ved in 21% cases that resolved within 3–4 days. One patient expired due to meningitis and septicemia. One patient had CSF leak that was effectively managed by placing lumbar drain. There was significant improvement in visual symptoms and hormonal levels. Average hospital stay was 13.54 days and mean follow up period was 13 months. EETS approach is safe, minimally invasive an...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research

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Source: PET Clinics - Category: Radiology Authors: Source Type: research
DIABETES symptoms aren ’t always obvious, but itching around the penis, wounds that are slow to heal and weight loss are all signs of the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This study, involving 140 patients with T2DM following percutaneous coronary intervention (PCI), evaluated the efficacy of aspirin upon concomitant use of prasugrel (10 mg/d) or ticagrelor (90 mg/d). Platelet reactivity was assessed by value of ADP‐induced light transmittance aggregometry (LTA) and vasodilator‐stimulated phosphoprotein phosphorylation‐platelet reactivity index (VASP‐PRI) at baseline, 7 and 30 days after randomized P2Y12 inhibitor treatment. ResultsThe study showed a decreased platelet reactivity after use of P2Y12 inhibitors (both P  .05). As for intragroup measurements, wh...
Source: Journal of Clinical Pharmacy and Therapeutics - Category: Drugs & Pharmacology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Authors: Zhou X, Xue F, Wang H, Qiao Y, Liu G, Huang L, Li D, Wang S, Wang Q, Li L, Li R Abstract OBJECTIVES: To assess the quality of life (QOL) and factors affecting QOL in hemodialysis patients so as to improve QOL of dialysis patients and provide the basis for better clinical care. METHODS: A retrospective study was performed to assess the QOL and factors affecting QOL in hemodialysis patients. We recruited 125 patients who had been receiving hemodialysis for at least 2 years in the dialysis units of nine hospitals in Shanxi Province, China, and conducted a multi-center questionnaire survey between 1...
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
(Int J Gynaecol Obstet. 2017;138(1):84–88) Trial of labor after cesarean (TOLAC) is often discouraged because of increased risk of adverse maternal and perinatal outcomes. However, few studies have focused on TOLAC with a subgroup of women with gestational diabetes mellitus (GDM), which is known to complicate pregnancies, for example increased risk of neonatal respiratory distress syndrome. In the present study, authors assess rates of TOLAC and subsequent vaginal birth after cesarean (VBAC) among women with GDM and identify associated factors.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
(Anesth Analg. 2017;124(3):879–886) Small studies have suggested that there is a difference in obstetric maternal morbidities between Asian American/Pacific Islanders (AAPIs) and Caucasian women, including higher rates of gestational diabetes, peripartum hemorrhage, perineal lacerations, and infections. However, no large nationwide epidemiologic study regarding this issue exists. Therefore, the authors of the present study analyzed data from the National Inpatient Sample (NIS) and compared comorbidities, severe maternal conditions, peripartum complications, and mortality between AAPI and Caucasian women.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research
This study aimed to evaluate the predictors of delayed surgical intervention in ASDH patients who are initially managed conservatively. Methods: From January 2007 to December 2015, 842 patients diagnosed with ASDH were treated at our institution. Among them, 158 patients with convexity ASDH were initially treated conservatively. Patients were divided into a delayed surgery group and a conservative group. Demographic characteristics, past medication and medical histories, and radiological and laboratory data were collected by retrospective chart review. Independent risk factors were identified with univariate and multiv...
Source: Journal of Korean Neurosurgical Society - Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research
Conclusion: We showed that diabetes mellitus, anticoagulation, headache, and preoperative midline shifting were independent predictors of recurrence of chronic subdural hematoma. PMID: 29142630 [PubMed]
Source: Journal of Korean Neurosurgical Society - Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research
Conclusion: Our clinical results showed that for single-level cases, plate fixation had no additional benefit versus cage-only; for two-level ACDF cases, the fusion rate and clinical outcomes were similar, although the cage-with-plate fixation group had a lower incidence of cage subsidence than did the cage-only group. We conclude that physicians should be aware of this possible disadvantage associated with using cervical plates in one-level ACDF. However, in two-level ACDF, subsidence is more likely to occur without plate fixation, and thus the addition of plate fixation should be considered. PMID: 29142629 [PubMed]
Source: Journal of Korean Neurosurgical Society - Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research
Conclusion: Increasing age might be an important risk factor for complications in patients undergoing PLIF, however, we would like to recommend that if the situation of spine of extreme geriatric patients need PLIF, it should be in the surgeon's consideration after careful selection and clinical judgement. PMID: 29142628 [PubMed]
Source: Journal of Korean Neurosurgical Society - Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research
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