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Villafa ña-founded artificial vessel developer Medical 21 looks to raise $15m

St. Jude Medical founder Manny Villafaña’s newest medtech play, Medical 21, is looking to raise $15 million in an equity round of funding, according to an SEC filing posted recently. The company is developing an artificial blood vessel as an alternative to harvesting blood vessels for coronary artery bypass surgeries, and has already begun animal testing of the technology, according to a Twin Cities Business report. Bypass surgeries, which are performed over 500,000 times a year in the US, require surgeons to harvest blood vessels from a patient’s body to be stitched into the heart to repair the circulatory system. The development of an artificial vessel could significantly change how the procedures are performed, according to the report – a goal that Medical 21 hopes to see to fruition. “People have tried for 40 or 50 years to do this and no one has done it. We figure we can save $10,000 to $20,000 per patient, not to mention the pain and rehabilitation. It’s a pursuit that has to be done. We keep tearing up people’s arms and legs and costing their healthcare system enormous dollars. So I’m going after the holy grail,” Villafaña told TCB. Medical 21 is using a new material developed by the University of Iowa and licensed to the company to make its artificial vessels, something Villafaña says gives him confidence, according to the report. The material consists of cellulose graft conduits supported by a thin ...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Cardiovascular medical21 Source Type: news

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_____ “The future is already here — it’s just not very evenly distributed” — William Gibson Last week we asked the question, Have you ever used–for yourself or for others–technologies or products that you think would fall into the category of brain enhancement? a) If Yes, what did you use and what lessons learned can you share? b) If No, what issues would you like to see addressed before considering doing so? Thank you everyone for your great answers and comments! They are very valuable in helping us finalize the agenda of the the upcoming 2017 SharpBrains Virtu...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Peak Performance Technology Alpha-Stim Anki app brain-enhancement brain-sensing Brain-Training Calm Calm app CBT-I dual n-back electrostimulation headband heartmath HRV biofeedback Source Type: blogs
AbstractSpinal cord compression is a complex and challenging condition that greatly affects the quality of life. Non-pharmacological techniques have only been studied to a very lesser extent; although they are evidence to be beneficial. We performed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) analysis of the scientific literature in several databases (Medline, Cochrane, Scopus, Cuiden, Pubmed, Lilacs and Embase); using the following keywords: spinal cord compression, spine compression, mobilization, positioning, brace and bracing. Eleven studies met the inclusion criteria and were finally in...
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
Abstract We studied 8 patients with spinal cord stimulation (SCS) devices which had been previously implanted to treat neuropathic chronic pain secondary to Failed Back Surgery Syndrome. The aim of our study was to investigate the effects of SCS on posture and gait by means of clinical scales (Short Form Health Survey-36, Visual Analogue Scale for pain, and Hamilton Depression Rating Scale) and instrumented evaluation with 3D Gait Analysis using a stereophotogrammetric system. The latter was performed with the SCS device turned both OFF and ON. We recorded gait and posture using the Davis protocol and also trunk m...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
This study cohort is a healthy subset of the EpiPath cohort, excluding all participants with acute or chronic diseases. With a mediation analysis we examined whether CMV titers may account for immunosenescence observed in ELA. In this study, we have shown that ELA is associated with higher levels of T cell senescence in healthy participants. Not only did we find a higher number of senescent cells (CD57+), these cells also expressed higher levels of CD57, a cell surface marker for senescence, and were more cytotoxic in ELA compared to controls. Control participants with high CMV titers showed a higher number of senes...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSIONS: The SiPAS questionnaire is able to quickly screen psoriasis patients for PsA. A SiPAS score ≥3 is an indication for referral to a rheumatologist. The SiPAS needs further validation. PMID: 29148421 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
AbstractThe purpose of the study was to assess the effectiveness of a specific rehabilitation therapy for chronic non-specific low-back pain patients, based on a random/irregular functional perturbation training induced by force disturbances to the spine. Forty patients (20 controls and 20 in the perturbation-based group) finished the whole experimental design. A random-perturbation exercise, which included variable and unpredictable disturbances, was implemented in the therapy of the perturbation-based group (13 weeks, two times per week and 1.5  h per session). The participants of the control group did not receive a...
Source: European Journal of Applied Physiology - Category: Physiology Source Type: research
Conclusion The spontaneous expulsion of a colonic lipoma is very rare. Our observation showed that this expulsion may be partial. +The changes that the lipoma undergoes can evoke a malignant cause. a supplement to take care of this eventuality is necessary.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conclusions Low dose TRO-CTA protocol using SAFIRE allows a high confidence diagnostic level with the benefit of a 34% radiation dose decrease compared with a standard TRO-CTA protocol using FBP.
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
Publication date: Available online 12 October 2017 Source:EXPLORE: The Journal of Science and Healing Author(s): Daniel A. Ostrovsky
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
I was teaching about subtle coronary occlusion at EKG conference to our residents a couple days ago.  About coronary occlusion that does not meet STEMI criteria and that many physicians would miss.They were asking me about whether, if they missed one of these, would they have missed a STEMI?I responded: " No, you would not have missed a STEMI, and you would not be blamed for anything,but you would have missed anopportunity to save the patient's heart. "Just as I was explaining this, a text message came through from a former resident, with this ECG and the question:" Diagnostic ECG? "What do yo...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
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