The body composition profile is associated with response to anti ‐TNF therapy in Crohn's disease and may offer an alternative dosing paradigm

ConclusionsIn this cohort study, body composition profiles did not correlate well with BMI. Myopenia was associated with primary nonresponse with potential implications for dosing and serves as an explanation for pharmacokinetic failure.

Source: Alimentary Pharmacology and Therapeutics - September 7, 2017 Category: Drugs & Pharmacology Authors: N. S. Ding, G. Malietzis, P. F. C. Lung, L. Penez, W. M. Yip, S. Gabe, J. T. Jenkins, A. Hart Tags: ORIGINAL ARTICLE Source Type: research