Severe Psoriasis Linked to Higher Risk of Earlier Death
Title: Severe Psoriasis Linked to Higher Risk of Earlier DeathCategory: Health NewsCreated: 9/5/2017 12:00:00 AMLast Editorial Review: 9/6/2017 12:00:00 AM
People with psoriasis can dye their hair safely. However, there are factors to consider before, during, and after applying the dye. In this article, learn about the risks, and seven tips developed to help people with psoriasis to dye their hair safely. We also describe how to prevent flare-ups on the scalp.
Both atopic dermatitis (AD) and psoriasis are characterized by complex inflammatory circuits that may be regulated through “feed-forward” mechanisms in the epidermis that amplify cellular immune responses through production of keratinocyte-derived cytokines and inflammatory mediators. IL-17C is a unique cytokine that is produced by keratinocytes and that is involved in such synergistic loops that may be responsible for amplifying the inflammation in both diseases. This may ultimately lead to induction of S100As and other molecules that accompany epidermal hyperplasia.
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Learn about the use of Janus kinase inhibitors, which have become promising treatment options for dermatologic conditions such as psoriasis, atopic dermatitis, alopecia areata, vilitigo, and more.Skin Therapy Letter
Inhibitory effects of TGP on KGF‑induced hyperproliferation of HaCaT cells via suppression of the p38 MAPK/NF‑κB p65 pathway. Mol Med Rep. 2018 Jun 15;: Authors: Pang W, Qi X, Cao C, Zhang S Abstract Psoriasis is a chronic inflammatory skin disease, primarily caused by overgrowth and abnormal differentiation of epidermal keratinocytes. Studies have suggested that keratinocyte growth factor (KGF) may be involved in the regulation of differentiation and development of keratinocytes. Total glucosides of peony (TGP) have been widely used for the treatment of psoriasis. The present study aimed to ...
Two-year-old Maisie Buchanan, from Falkirk, was hospitalised last year and diagnosed with severe psoriasis which makes her entire body go bright red and gives her scaly, dry patches of skin.
Abstract: Graft-versus-host disease (GVHD) is the primary cause of morbidity and non–relapse-related mortality after hematopoietic stem cell transplantation. GVHD is classically divided into acute and chronic forms; acute cutaneous GVHD presents as a morbilliform eruption, whereas chronic cutaneous GVHD presents with lichen planus–like or sclerodermoid morphology. Psoriasiform GVHD is a rarely described subtype that is challenging to distinguish clinically from psoriasis. In addition to classic psoriasiform histologic findings, demonstration of an often subtle vacuolar interface dermatitis and lymphocyte sate...
Prescriber,Volume 29, Issue 6, Page 32-34, June 2018.
•Based on nonlinear multivariate algorithms, IL-17F is the most important predictor of PASI improvement with apremilast, and nonlinear synergistic cytokine effects are more predictive of PASI response to apremilast than linear univariate models.
Topical administration permits targeted, sustained delivery of therapeutics to human skin. Delivery to the skin, however, is typically limited to lipophilic molecules with molecular weight of