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Hi There, I Write Your Stories, I Mean ‘Our Stories’

I write stories about my coworkers. Collectively known as "Our Stories," a new one publishes in my organization's newsletter every other week. Yesterday, the newsletter published a story I wrote about . . . myself. Here is that story with some redactions.* * *Every morning after waking, I prime my body and mind for the day: meditate for 20 minutes, perform 20 pull ­-ups, and then jump on a mini trampoline while singing whatever pops into my head. I then move to the kitchen where I prepare four eggs mixed with hot sauce and grated cheddar on a pan coated with butter, and pour-­over coffee. Once my breakfast is ready, I enjoy it at my desk while reading the n ews. Fifteen minutes later, I set the empty plate aside, bring my mug closer, and repeat a mantra that primes me for what comes next: writing. No email, notifications or distractions of any kind, just writing.I thrive on routines. If my day consists of writing, coffee and an adventure, then that ’s a perfect day I could live repeatedly. Photo taken on July 2, 2017, while hiking with friends at Mary’s Rock in Shenandoah National Park, Virginia. In the photo I am holding forearm crutches which give me freedom to explore the world despite not having a left hip bone. Photo by Heather Durosk o.Writing is solitary. It ’s just me, a giant coffee mug, a laptop, and Daft Punk playing through my 15-watt Bluetooth speaker.This is my craft, which I chose without realizing it. That unconscious decisi...
Source: cancerslayerblog - Category: Cancer & Oncology Tags: life lessons writing/speaking Source Type: blogs

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This study investigated the role of miR‐339‐5p involvement in lung carcinoma cell lines and chemoresistance to Taxol. We observed that miR‐339‐5p was significantly downregulated in Taxol‐A549 cells compared with A549 cells. In vitro studies further indicated that miR‐339‐5p could promote colony formation and attenuate apoptosis of lung carcinoma cell lines through targeting α1,2‐fucosyltransferase 1 and regulation of the downstream protein Lewis y. Furthermore, miR‐339‐5p was found to enhance the proliferation inhibition ability of Taxol in lung carcinoma cell lines as well as in the Taxol‐A549 ...
Source: IUBMB Life - Category: Research Authors: Tags: Research Communication Source Type: research
ABSTRACT It is widely accepted that the cell of origin of breast cancer is the adult mammary epithelial stem cell, however demonstrating the presence and location of tissue stem cells in the human breast has proved difficult. Furthermore, we do not know the clonal architecture of the normal and premalignant mammary epithelium or its cellular hierarchy. Here we use deficiency in the mitochondrial enzyme cytochrome c oxidase (CCO), typically caused by somatic mutations in the mitochondrial genome, as a means to perform lineage tracing in the human mammary epithelium. PCR sequencing of laser‐capture microdissected cells in ...
Source: The Journal of Pathology - Category: Pathology Authors: Tags: Original Paper Source Type: research
Abstract This correction is being published to correct Fig. 2B in above article. PMID: 28934832 [PubMed - in process]
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract Recently, the incidence of upper third gastric cancer has increased, and with it the number of endoscopic submucosal dissection (ESD) procedures performed has been increasing. However, if ESD is not indicated or non-curable, surgical treatment may be necessary. In the case of lower third gastric cancer, it is possible to preserve the upper part of the stomach; however, in the case of upper third gastric cancer, total gastrectomy is still the standard treatment option, regardless of the stage. This is due to the complications associated with upper third gastric cancer, such as gastroesophageal reflux after...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract The cases of non-curative endoscopic resection (NCR) of early gastric cancer have increased due to the widespread use of endoscopic submucosal dissection (ESD). NCR is associated with augmenting chances of local recurrence and lymph node metastasis (LNM). Therefore, some additional treatment strategies after NCR are needed. Treatment strategies for NCR should be determined by considering the risk of residual tumor or local recurrence and LNM. Additional surgical treatment such as gastrectomy and lymph node dissection are recommended in patients who have high-risk of LNM. Close observation without addition...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract Endoscopic resection (Endoscopic mucosal resection [EMR] and endoscopic submucosal dissection [ESD]) is already established as a first-line treatment modality for selected early gastric cancer (EGC). In Korea, the number of endoscopic resection of EGC was explosively increased because of a National Cancer Screening Program and development of devices and techniques. There were many reports on the short-term and long-term outcomes after endoscopic resection in patients with EGC. Long-term outcome in terms of recurrence and death is excellent in both absolute and selected expanded criteria. Furthermore, endo...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract Gastric adenoma (dysplasia) is a precancerous lesion. Therefore, managements of gastric adenomas are important for preventing the development of gastric cancers and for detecting gastric cancers at earlier stages. The Vienna classification divides gastric adenomas into two categories: high-grade dysplasia and low-grade dysplasia. Generally, endoscopic resection is performed for adenoma with high-grade dysplasia due to the coexistence of carcinoma and the potential of progression to carcinomas. However, the treatments of adenoma with low-grade dysplasia remain controversial. Currently two treatment strateg...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract Background/AimsThe operative link for gastritis assessment (OLGA) and operative link on gastric intestinal metaplasia assessment (OLGIM) staging systems are recommended to assess the severity of gastritis, but the optimal biopsy sites have not been clearly defined. We aimed to investigate whether the scoring of the OLGA and OLGIM stages was affected by the use of different biopsy sites. MethodsBetween 2014 and 2015, to determine OLGA and OLGIM stages, seven biopsy samples were obtained from the antrum (lesser and greater curvatures [LG] of the antrum and lesser curvature of the angle) and corpus (LG and anterior a...
Source: Helicobacter - Category: Gastroenterology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Recent strides in cardiovascular medicine have produced an evident prolongation of life. Thus, cancer mortality, the second leading cause of death, is closely rivalling that from circulatory diseases [1]. Death rates from colorectal cancer (CRC) are second only to lung cancer in men and breast cancer in women [1]. North Americans and Europeans are more prone to CRC than the rest of the world, with an estimated lifetime risk of 5% [2]. Adenomas, the precursors of most CRC, are estimated to occur in 20 –50% of Western individuals older than 50years [2].
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
Evidence regarding the chemo-protective effects of aspirin has influenced expert opinion in favour of low-dose aspirin use in certain patient populations without cardiovascular disease (CVD). The effects of aspirin in reducing the incidence of colorectal cancer (CRC) may be a large contributor to this favourable risk –benefit profile of low-dose aspirin in primary CVD prevention.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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