Many Moisturizers Aren't What They Claim to Be
WEDNESDAY, Sept. 6, 2017 -- Many skin moisturizers that claim to be fragrance-free or hypoallergenic are not, and may aggravate skin disorders such as psoriasis and eczema, a new study says. Northwestern University researchers examined the top 100...
Summary Atopic dermatitis (eczema) is a chronic, and sometimes debilitating, inflammatory skin disease which causes itching and damaged skin barrier function. Current treatments include topical (applied to the skin) corticosteroids and calcineurin inhibitors such as tacrolimus; unfortunately long‐term use of topical corticosteroids may cause thinning of the skin and tacrolimus can be irritant. Kinases are enzymes that are important to many roles of cells within the body, and the Janus Kinase (JAK) pathway plays a role in inflammation. In recent years, medicines that inhibit this pathway have been developed, with potentia...
Publication date: Available online 9 February 2018 Source:Microbial Pathogenesis Author(s): Adriana Christie Lacerda Simões, Tinara Leila de Souza Aarão, Jorge Rodrigues de Sousa, Diogo Lima Prudente, Yaisa Gomes de Castro, Rodrigo Bona Maneschy, Hellen Thais Fuzii, Juarez Antonio Simões Quaresma Parvovirus B19 (PVB19) is a virus found in the skin that causes asymptomatic infections and can exist in the host for long periods to time. The virus induces a local inflammatory response and is associated with the development of arthritis and other autoimmunes diseases. Parvovirus B19 DNA was investigated by...
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To examine the epidemiology of eczema herpeticum (EH), a condition characterized by viral infection concomitant with a preexisting inflammatory dermatosis, Hsu and colleagues assessed more than 5 million pediatric discharge records from 11 years of nationwide inpatient data in the United States. Non-whites, especially Asians, were at increased risk for hospitalization for EH. Other risk factors included younger age, location in metropolitan areas, and higher income quartiles. While mortality was minimal, comorbidities included atopic dermatitis, psoriasis, asthma, eye infections, bacterial/fungal infections, and septicemia.
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In this study, a moisturizer with 7% sweet almond oil and 2% colloidal oatmeal was found to be both safe and effective in treating patients with moderate to severe hand dermatitis. J Drugs Dermatol. 2018;17(1):78-82.. PMID: 29320591 [PubMed - in process]