Effects of anaesthesia and analgesia on long-term outcome after total knee replacement: A prospective, observational, multicentre study

CONCLUSION: Continuous regional anaesthesia provides analgesic benefit for up to 1 month after surgery, but did not influence PPSP at 6 months. Better pain control at 1 month was associated with reduced PPSP. Patients with higher expectations from surgery, enhanced basal inflammation and a pessimistic outlook are more prone to develop PPSP. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT02147730
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Pain Source Type: research