'Listen to women': UK doctors issued with first guidance on endometriosis

Disease, which causes crippling pain and can lead to infertility, affects 176 million women worldwide and currently takes seven to eight years to diagnoseYears of pain, but no diagnosis: one woman ’s experience of endometriosisDoctors are being advised to listen to what women tell them about crippling pelvic and period pain and look out for the symptoms of endometriosis in a bid to speed up diagnosis of a disease that can wreck lives and careers.It takes an average of seven to eight years to be diagnosed with endometriosis, according to the first-ever guidance on managing a disease that affects one in 10 women from the National Institute for Health and Care Excellence (Nice) in England. Experts say the long wait is the same all over the western world. Many women are told they are making a fuss about normal period pain. Some are unable to work and the disease causes others to become infertile.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Endometriosis Health Society The National Institute for Health and Care Excellence (Nice) NHS Women Sexual health Menstruation Source Type: news

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Endometriosis, classically defined as a disease of unknown origin that causes pain and infertility, has an estimated incidence of approximately 10% in women of reproductive age. Several epidemiologic factors are associated with an increased incidence, such as an early age at menarche and short menstrual cycle length. Conversely, current use of oral contraceptives and multiparity are characteristics associated with a lower incidence. It also is interesting that an inverse correlation between body mass index and incidence of endometriosis has been observed by numerous reports.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
Endometriosis is a very common finding in infertile women and is one of the most controversial topics. This is true for multiple reasons. For example, lots of patients with endometriosis have no symptoms at all, and this is an incidental finding either on a vaginal ultrasound scan, which picks up a chocolate cyst, or on a diagnostic laparoscopy done for checking infertility. Now, on an ultrasound scan or a laparoscopy, once the diagnosis is made, then doctors usually get itchy fingers and want to treat it. The treatment is usually doing an operative laparoscopy to remove the lesion, but whether this actually helps the pati...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Authors: Vassilopoulou L, Matalliotakis M, Zervou MI, Matalliotaki C, Spandidos DA, Matalliotakis I, Goulielmos GN Abstract The aim of the present review was to discuss a matter of concern in the clinical field of obstetrics/gynecology, namely the potency of in vitro fertilization (IVF) in the management of endometriosis-associated infertility. Endometriosis is a medical condition affecting one tenth of women in their fertile years, and accounts for up to 50% of infertile women. Thus, such high prevalence has established the necessity for investigating the effectiveness of available techniques in eradicating the di...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: Available online 11 August 2018Source: Autoimmunity ReviewsAuthor(s): Tao Zhang, Caterina De Carolis, Man Gene Chi-Wai, Chi-Chiu WangAbstractEndometriosis (EMS), an estrogen-dependent inflammatory disorder affects approximately 5–10% of the general female population of reproductive age and 20–90% of women with pelvic pain and infertility. Many immunological factors are known to contribute significantly to the pathogenesis and pathophysiology of EMS, and both chronic local inflammation and autoantibodies in EMS shares many similarities with autoimmune diseases (AD). However, the autoimmune etio...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Conclusion: Serum caspase-3 level may be a reliable predictor of endometriosis severity.Gynecol Obstet Invest
Source: Gynecologic and Obstetric Investigation - Category: OBGYN Source Type: research
US regulators approve new treatment for reducing pain from endometriosis, a common condition that can cause infertility
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
ConclusionModerate-to-severe endometriosis was more common in women with East or South East Asian ethnicity in our tertiary referral center. This could be explained by East/South East Asians with minimal-mild disease being less likely to seek care, or genetic/environmental differences that increase the risk of more severe disease amongst East/South East Asians.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: August 2018Source: Gynecologic Oncology Reports, Volume 25Author(s): Lisa N. Abaid, John S. Cupp, Miles Chang, Steven R. Beanes, Bram H. GoldsteinAbstractEndometriosis is a condition wherein an ectopic layer of endometrial tissue arises in an extra-uterine location, often effecting significant pelvic pain and infertility. While very uncommon, there have been reported cases of endometriosis undergoing malignant transformation, frequently involving the ovaries and seldom in extra-gonadal regions. We recount a case depicting a 63 year-old woman who presented with an apparent inguinal hernia in 2017; she wa...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
Publication date: Available online 14 February 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Bansari G. Patel, Emily E. Lenk, Dan I. Lebovic, Yimin Shu, Jie Yu, Robert N. TaylorAbstractDespite an estimated prevalence of 11% in women and plausible historical descriptions dating back to the 17th century, the etiology of endometriosis remains poorly understood. Classical theories of the histological origins of endometriosis are reviewed below. Clinical presentations are variable, and signs and symptoms do not correlate well with the extent of disease. In this summary, we have attempted...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Publication date: June 2018Source: Best Practice &Research Clinical Endocrinology &Metabolism, Volume 32, Issue 3Author(s): Ioannis Simitsidellis, Douglas A. Gibson, Philippa T.K. SaundersEndometriosis is a chronic incurable disorder that affects 1 in 10 women of reproductive age: associated symptoms include chronic pain and infertility. The aetiology of endometriosis remains poorly understood but patients, clinicians and researchers are all in agreement that new non-surgical therapies are urgently needed to reduce the severity of symptoms. Preclinical testing of drugs requires the development and validation of mod...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
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