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Intensive BP Lowering in Chronic Kidney Disease Associated with Lower Mortality (FREE)

By Joe Elia Edited by David G. Fairchild, MD, MPH Intensive blood-pressure lowering among hypertensive patients with moderate- to late-stage kidney disease is associated with lower all-cause mortality, a meta-analysis finds. …
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news

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Authors: Gallant J, Hsue P, Budd D, Meyer N Abstract OBJECTIVE: To estimate the incremental healthcare utilization and costs associated with common non-infectious comorbid conditions among commercially and Medicaid-insured HIV-infected patients in the US. METHODS: US administrative claims were used to select adult HIV patients with chronic kidney disease (CKD), cardiovascular disease (CVD) events, or fracture/osteoporosis, three common comorbidities that have been associated with HIV and HIV treatment, between 01/012004 and 06/30/2013. Propensity score matched controls with no CKD, no CVD events, no fracture/os...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
We examined data from various studies in India and elsewhere using generic DAAs, and evaluated whether they are equally efficacious as the branded drugs. Since the availability of generic DAAs in the Indian market, there is a lot of real life data as well as prospective studies in special patient populations such as hematological disorders (thalassemia and hemophilia), chronic kidney disease, hemodialysis patients, post liver and renal transplant patients on immunosuppression, intravenous drug users, confections and other high risk groups. Control of HCV infection in India requires multi pronged approach. There is a need t...
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
Venous outflow obstructions are rare anatomic findings that can present with symptoms of elevated intracranial pressure, including headache and vision loss, and can be mistaken for more common diagnoses, such as idiopathic intracranial hypertension (IIH) or cerebral venous sinus thrombosis (CVST). While venous outflow obstructions have been reported in rare bone dysplasias and congenital abnormalities, to date they have not been reported in renal osteodystrophy (ROD), a relatively common disorder seen in patients with chronic kidney disease.
Source: World Neurosurgery - Category: Neurosurgery Authors: Tags: Case Report Source Type: research
Conclusions Elevated baseline proteinuria was the only predictor for PC-AKI in patients undergoing renal artery stent placement. Patients who developed PC-AKI were not at greater risk for hemodialysis or death.
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
This study aimed to comprehensively assess the effects of exercise on cardiopulmonary function indices in patients with chronic kidney disease (CKD). A literature review was performed by searching literatures in PubMed and Embase before June 2016. Studies were selected based on predefined inclusion and exclusion criteria, followed by data extraction and a quality assessment of the included studies using the Cochrane Collaboration's tool. Correlations between exercise and cardiopulmonary function indices [pulse wave velocity, respiratory exchange ratio, and peak oxygen uptake (VO2 peak)] were then evaluated using mean diffe...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
This article provides a detailed overview of the molecular mechanisms which cause dyslipidemia and the nature of lipid disorders associated with CKD and ESRD. PMID: 28930541 [PubMed - in process]
Source: Atherosclerosis - Category: Cardiology Authors: Tags: Front Biosci (Landmark Ed) Source Type: research
Previously, we showed that patients undergoing carotid endarterectomy have an increased risk for major atherosclerotic events in the presence of moderate or poor kidney function. Acceleration of vascular inflammatory responses is considered to be causally involved in progression of atherogenesis and poor outcome in chronic kidney disease patients. The association between kidney function and plaque composition has not been thoroughly investigated yet. The aim of this study was to investigate the association between kidney function and atherosclerotic plaque composition in patients undergoing carotid endarterectomy.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
BackgroundBecause chronic kidney disease (CKD) is a worldwide problem, accurate pathological and functional evaluation is required for planning treatment and follow‐up. Intravoxel incoherent motion diffusion‐weighted imaging (IVIM‐DWI) can assess both capillary perfusion and tissue diffusion and may be helpful in evaluating renal function and pathology. PurposeTo evaluate functional and pathological alterations in CKD by applying IVIM‐DWI. Study TypeProspective study. SubjectsIn all, 72 CKD patients who required renal biopsy and 20 healthy volunteers. Field Strength1.5T. AssessmentAll subjects underwent IVIM‐DWI ...
Source: Journal of Magnetic Resonance Imaging - Category: Radiology Authors: Tags: Original Research Source Type: research
Conclusions: The maternofetal outcomes in patients with kidney transplantation are comparable with those of nontransplanted CKD patients with similar levels of kidney function impairment and progressive and/or immunologic kidney disease.
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science-General Source Type: research
This article reviews medication related problems associated with CKD, including nonadherence and medication reconciliation.U.S. Pharmacist
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news
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