Log in to search using one of your social media accounts:


Intensive BP Lowering in Chronic Kidney Disease Associated with Lower Mortality (FREE)

By Joe Elia Edited by David G. Fairchild, MD, MPH Intensive blood-pressure lowering among hypertensive patients with moderate- to late-stage kidney disease is associated with lower all-cause mortality, a meta-analysis finds. …
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news

Related Links:

Authors: Wang H, Li Z, Guo X, Chen Y, Chen S, Tian Y, Sun Y Abstract BACKGROUND: Despite current interest in the unfavorable impact of nontraditional lipid profiles on cardiovascular disease, information regarding its relations to reduced glomerular filtration rate (GFR) in H-type hypertension population has not been systemically elucidated. METHODS: Analyses were based upon a cross-sectional study of 3259 participants with H-type hypertension who underwent assessment of biochemical, anthropometric, and blood pressure values. Reduced GFR was considered if meeting estimated GFR
Source: Annals of Medicine - Category: Internal Medicine Tags: Ann Med Source Type: research
We examined the association of pro-ENK with eGFR and UAE as a markers of CKD. METHODS: We included 4,375 subjects of the Prevention of Renal and Vascular End-Stage Disease (PREVEND) study. CKDeGFR was defined as development of eGFR 30 mg/24h. RESULTS: Baseline median pro-ENK was 52.2 (IQR: 44.9-60.5) pmol/L. After a median follow-up of 8.4 (IQR: 7.9-8.9) years, 183 subjects developed CKDeGFR and 371 developed CKDUAE. The association of pro-ENK with CKDeGFR was modified by sex (Pinteraction
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research
ConclusionLow levels of parathyroid hormone before transplantation were associated with increased risk of post-transplant vascular events both in patients with and without pre-transplant parathyroidectomy. Any conclusions on causal or direct effect of PTH on outcome cannot be drawn from this observational study.
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
FRIDAY, Feb. 23, 2018 -- Chronic kidney disease may affect brain function in children and teens, especially those on dialysis, researchers say. Results of their study review suggest academic assistance may be needed in specific areas, including...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusions In this case-control, survey-based study, the prevalence of nephrolithiasis was 2 times higher in patients with CLD.
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
AbstractMany cardiovascular diseases present renin –angiotensin–aldosterone system (RAAS) hyperactivity as an important pathophysiological mechanism to be target in the therapeutic approaches. Moreover, arterial stiffness is currently considered as a new independent risk factor for cardiovascular disease in different clinical conditions, includi ng hypertension and chronic kidney disease. In fact, excessive stimulation of angiotensin type 1 (AT1) receptors, as well as mineralocorticoid receptors, results in cellular growth, oxidative stress and vascular inflammation, which may lead to arterial stiffness and acc...
Source: High Blood Pressure and Cardiovascular Prevention - Category: Cardiology Source Type: research
There is a large and growing burden of diabetes globally. In 2013, 382 million people had diabetes and this number has been projected to increase to 592 million by 2035 [1]. With increasing life expectancy and prevalence of type 2 diabetes, complications and deaths attributable to diabetes will also increase, especially if there is no concomitant improvement in the health system for its early management [1]. Chronic kidney disease (CKD) is a common complication in people with type 2 diabetes [2] and may in some cases progress to end-stage renal disease, which requires dialysis and/or kidney transplant which are associated ...
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
Source: International Journal of Nursing Studies - Category: Nursing Authors: Tags: Cochrane Nursing Care Field (CNCF) – Cochrane Review Summary Source Type: research
ConclusionOur results prompt another mechanism of anti-fibrotic renal protection of renalase, which may be partly associated with inhibiting oxidative stress. These data provided another theoretical basis that supplementation with exogenous renalase may be a promising strategy for slowing or halting the progression of CKD.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
Conclusion: CKD is frequent at PAH diagnosis and is independently associated with increased mortality. Right heart failure may induce renal hypoperfusion and congestion, and is associated with eGFR decrease.Am J Nephrol 2018;47:134 –143
Source: American Journal of Nephrology - Category: Neurology Source Type: research
More News: Chronic Kidney Disease | Primary Care | Urology & Nephrology