Severe Psoriasis Tied to Risk of Earlier Death
But experts say there may be ways to reduce those odds
Disease duration joins severity as a factor driving CV risk in patients with psoriasis, but the right therapy can lower this risk.Medscape Dermatology
Condition: Psoriasis Vulgaris Interventions: Drug: ethosomal preparation of anthralin; Drug: liposomal preparation of anthralin Sponsor: Assiut University Not yet recruiting
People with the skin disease psoriasis are at increased risk for type 2 diabetes, and the more severe the psoriasis, the greater their risk, a new study finds.
Source: HealthDay Related MedlinePlus Pages: Diabetes, Psoriasis
Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation
The authors of this study explain that secukinumab has demonstrated significant efficacy with a good safety profile through 1 year in the treatment of plaque psoriasis. They set out to determine the long-term (3-year) efficacy and safety of secukinumab in moderate-to-severe psoriasis. In total, 168 patients receiving secukinumab 300 mg on a fixed-interval schedule, and 172 receiving secukinumab 300 mg retreatment as needed entered this extension study. Secukinumab 300 mg fixed interval sustained high efficacy: at the end of year 3, the proportion of responders achieving ≥ 90% improvement in Psoriasis Area and Severity I...
Not only can stress trigger psoriasis flare-ups, but living with psoriasis can have an effect on a person's overall mental health. Learn more.
Can the active cannabinoids in cannabis be an effective treatment for itchy and painful psoriasis? We look at the evidence in this article.
Discussion Fats and fatty acids are essential for good human health. Saturated fats have hydrogen pairs linked to each carbon on the carbon backbone. They are solid or semi-solid at room temperature. Common examples are butter, lard, or hardened vegetable shortening. They are linked to higher cholesterol and triglycerides and only a small amount of them are recommended to be consumed in the diet. Unsaturated fats have one or more hydrogen atoms missing from the carbon backbone. They are liquid at room temperature. Monounsaturated fatty acids have one hydrogen pair that is missing from the carbon backbone. They are liq...
Plasmacytoid dendritic cells (pDCs) were described to accumulate in the skin of patients with psoriasis and to be recruited into the dermis upon allergen challenge in atopic dermatitis. Importantly, activation of pDCs in the skin has been identified as important initiator of psoriasis development. RNase 7 is one of the major antimicrobial peptides (AMP) secreted by keratinocytes and is expressed in significantly higher amounts in lesional skin of patients with atopic dermatitis or psoriasis than in healthy individuals.