Prostate Cancer: Symptoms, Tests, and Treatment

September is Prostate Health Awaremeness month. Prostate cancer is the second most common cause of cancer-related deaths among American men. Learn more.
Source: FDA Consumer Health Information Updates - Category: Consumer Health News Source Type: news

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PROSTATE cancer symptoms can be difficult to spot in its early stages, but usually affect the way you pass urine. You could be at risk of the disease ’s signs and symptoms if you use the toilet more often - how many times do you go for a wee every day?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
(Rutgers University) A recent study has found that a specific gene in cancerous prostate tumors indicates when patients are at high-risk for the cancer to spread, suggesting that targeting this gene can help patients live longer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
The objective of this study was to determine the impact of intravenous (IV) acetaminophen when added to the perioperative analgesic regimen for robotic-assisted laparoscopic prostatectomy (RALP) on hospital length of stay (LOS), postoperative pain scores, and opioid consumption. In this prospective, randomized, double-blind, placebo-controlled trial, a total of 86 patients undergoing RALP were prospectively enrolled and randomly assigned to receive either 1 g IV acetaminophen (study group; n = 43) or IV placebo (n = 43) within 15 minutes following the induction of anesthesia and pr...
Source: Journal of Pain and Palliative Care Pharmacotherapy - Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Conclusion Frequently observed, the nodular, oval and longitudinal (nodular, thick or with oval parts) shape of CG, especially of the thicker left CG, on MR scans may cause mistaking them for lymph nodes, even abnormal or metastatic. On whole-body PET/MRI, evident and sometimes high 68Ga-PSMA-11 uptake in CG increases the risk of a misinterpretation of them as metastases.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research
ConclusionMetastatic prostatic carcinoma to CNS demonstrates expression patterns consistent with particularly aggressive behavior. Lower ERG expression in dural and intraparenchymal metastases suggests a possibility that ERG-negative tumors with loss of MAP3K7 may become resistant to standard therapies and diffusely metastasize.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
Jo-Fan Chang, Jui-Ling Hsu, Yi-Hua Sheng, Wohn-Jenn Leu, Chia-Chun Yu, She-Hung Chan, Mei-Ling Chan, Lih-Ching Hsu, Shih-Ping Liu, Jih-Hwa Guh
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
[Evolution of the number of incident cases, stage and first treatments for prostate cancer in France between 2001 and 2016]. Prog Urol. 2019 Jan 08;: Authors: Delporte G, Olivier J, Ruffion A, Crouzet S, Cavillon C, Helfrich O, Leroy X, Villers A Abstract INTRODUCTION: No studies of French hospital registries for prostate cancer (PCa) have been published since the 2012 USPSTF recommendations. MATERIAL: This is a multicenter cohort study based on hospital data of prostate biopsies (PB) in 3 health centers between 2001 and 2016. The main objective is to describe the evolution of i...
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Authors: Murdica V, Mancini G, Loberto N, Bassi R, Giussani P, Di Muzio N, Deantoni C, Prinetti A, Aureli M, Sonnino S Abstract Prostate cancer (PC) is one of the most common leading causes of cancer-related death in men. Currently, the main therapeutic approaches available for PC are based on the androgen deprivation and on radiotherapy. However, despite these treatments being initially effective in cancer remission, several patients undergo recurrence, developing a most aggressive and resistant PC.Emerging evidence showed that abiraterone acetate drug will reduce PC recurrence by a mechanism independent of the in...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Nicolotti DG, Finessi M, Guarneri A, Pilati E, Giunta F, Deandreis D Abstract PMID: 30644307 [PubMed - as supplied by publisher]
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Authors: Beheshti M, Heinzel A, von Mallek D, Filss C, Mottaghy FM Abstract Defining an optimal therapeutic approach in metastatic castration-resistance prostate cancer (mCRPC) patients in advanced stages is still challenging in routine clinical practice. Prostate- specific membrane antigen (PSMA) targeted radionuclide therapy with β- or α-emitters such as 177-Lutethium (177Lu) or 225-Actinium (225A) has been a main focus at multiple academic researche centers in the last few years. This review article provides an overview of PSMA characteristics, clinical performance, safety and toxicity of PSMA targete...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
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