Hypersomnia and cognitive impairment in a patient with bipolar disorder - a case report.

CONCLUSIONS: The presence of daytime sleepiness, unremitting despite the modification of treatment, indicates the need for diagnostic screening for OSA, which can mimic some of the symptoms of depression, increase the risk of complications during anesthesia, and can be one of the causes of drug resistance. In addition to the negative impact of obstructive sleep apnea on the course of bipolar disorder, OSA also causes significant cognitive impairment in terms of attention and vigilance, long-term semantic and visual memory as well as visual-spatial and executive functions. PMID: 28866718 [PubMed - in process]
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research

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Authors: Barton BB, Segger F, Fischer K, Obermeier M, Musil R Abstract Introduction: Antipsychotic-induced weight-gain (AIWG) is a very important, yet often neglected side-effect in the treatment with first and second generation antipsychotics. AIWG can increase the risk of developing metabolic syndrome, diabetes and cardiovascular disease. Meta-analyses mostly concentrate on AIWG in schizophrenic and bipolar patients, even though antipsychotics are prescribed off-label across many other diagnostic groups (e.g. anxiety disorders, depression, autistic disorder).Areas covered: Pub Med and Web of Science were systemat...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
In this study, we discovered that chronic alcohol treatment increased editing of RNA of 5-HT2CR via up-regulating the expression of ADAR2, consequently reducing the release of ATP from astrocytes induced by 5-HT2CR agonist, MK212. Moreover, SSRI antidepressant fluoxetine decreased the expression of ADAR2 through the transactivation of EGFR/PI3K/AKT/cFos signalling pathway. The increased release of astroglial ATP by MK212 which was suppressed by chronic alcohol consumption, and reduction in ADAR2 activity eliminated the RNA editing of 5-HT2CR increased by alcohol in vitro and recovered the release of ATP from astrocytes ind...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
This article includes references to self-injury, intravenous drug use and disordered eating.* One in five US high school students have reported being bullied. Approximately 160,000 teenagers have skipped school as a preventative measure. I encountered bullies for the first time in second grade, in the midst of such an innocent time of my youth. I dreaded entering my elementary school classroom, as I was well aware of what my presence would entail. I endured both verbal and physical harassment from my fellow peers for nearly a decade. I was passive, inevitably leading to the acceptance of my “fate,” in addition ...
Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Anorexia Bullying Depression Eating Disorders Personal Stories Substance Abuse Addiction Recovery Anorexia Nervosa Drug Use heroin Self Harm Self Injury Source Type: news
The risk of developing bipolar disorder was increased in women with PCOS, possibly because of shared inflammatory pathways, a study has found; metformin may have a protective effect.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Ob/Gyn & Women ' s Health News Source Type: news
Authors: Augstburger E, Héron E, Abanou A, Habas C, Baudouin C, Labbé A Abstract Ischemic optic neuropathies are among the leading causes of severe visual acuity loss in people over 50 years of age. They constitute a set of various entities that are clinically, etiologically and therapeutically different. Anatomically, it is necessary to distinguish anterior and posterior forms. From an etiological point of view, the diagnosis of the arteritic form due to giant cell arteritis requires emergent management to prevent blindness and even death in the absence of prompt corticosteroid treatment. When this d...
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
RESUMO Os pacientes com s índrome do desconforto respiratório agudo requerem estratégias ventilatórias que demonstraram ser importantes na redução da mortalidade em curto prazo, como ventilação protetora e ventilação em posição prona. No entanto, os pacientes que sobrevivem têm permanência prolongada, tanto na unidade de terapia intensiva como no hospital, e experimentam redução na satisfação global com a vida (independência, aceitação e perspectiva positiva), na saúde menta...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
BACKGROUND: Suicide is a leading cause of death among adolescents in North America. Youth who present to the Emergency Department (ED) with acute suicidality are at increased risk for eventual death by suicide, thereby presenting an opportunity for seconda...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Adolescent-onset depression and anxiety represent a substantial, and growing, health-care burden. Unfortunately, traditional treatments for depression and anxiety that are effective in adults have small success rates in paediatric populations. 1 Theref...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Authors: Ferini-Strambi L, Sforza M, Poletti M, Giarrusso F, Galbiati A Abstract Excessive Daytime Sleepiness (EDS) is a common condition with a significant impact on quality of life and general health. A mild form of sleepiness can be associated with reduced reactivity and modest distractibility symptoms, but more severe symptomatic forms are characterized by an overwhelming and uncontrollable need to sleep, causing sudden sleep attacks, amnesia and automatic behaviors. The prevalence in the general population is between 10 and 25%. Furthermore, EDS has been considered a core symptom of obstructive sleep apnea (OS...
Source: Medicina del Lavoro - Category: Occupational Health Tags: Med Lav Source Type: research
CONCLUSIONS: BD are defined by several sleep and circadian rhythm abnormalities during all phases of the disorder. These abnormalities and disorders, especially during remitted phases, should be characterized and diagnosed to reduce mood relapses, treatment resistance and improve BD outcomes. PMID: 27669996 [PubMed - as supplied by publisher]
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
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