Longitudinal diffusion changes following postoperative delirium in older people without dementia

Conclusions:
Our study raises the possibility that delirium has an effect on the development of brain microstructural abnormalities, which may reflect brain changes underlying cognitive trajectories. Future studies are warranted to clarify whether delirium is the driving factor of the observed changes or rather a correlate of a vulnerable brain that is at high risk for neurodegenerative processes.

Source: Neurology - September 4, 2017 Category: Neurology Authors: Cavallari, M., Dai, W., Guttmann, C. R. G., Meier, D. S., Ngo, L. H., Hshieh, T. T., Fong, T. G., Schmitt, E., Press, D. Z., Travison, T. G., Marcantonio, E. R., Jones, R. N., Inouye, S. K., Alsop, D. C., On behalf of the SAGES Study Group Tags: MRI, DWI, Delirium, Cognitive aging ARTICLE Source Type: research