Mechanism of impaired afferent arteriole myogenic response in Dahl salt sensitive rats: role of 20-HETE.
In conclusion, Dahl SS have an impaired myogenic response and ATP-induced Af-Art constriction due to a decrease in Af-Art 20-HETE. The impaired myogenic responses may contribute to the nephrosclerosis that develops in Dahl SS.
PMID: 24990891 [PubMed - as supplied by publisher]
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Ren Y, D'Ambrosio MA, Garvin JL, Peterson EL, Carretero OA Tags: Am J Physiol Renal Physiol Source Type: research
More News: Perfusion | Urology & Nephrology