Interactive Roles of CD73 and Tissue Non-Specific Alkaline Phosphatase in the Renal Vascular Metabolism of 5'-AMP.
Conclusion: CD73 and TNAP play interactive roles to metabolize luminally applied 5'-AMP in the renal vasculature such that inhibition of both is required to inhibit the production of adenosine.
PMID: 24990899 [PubMed - as supplied by publisher]
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Jackson EK, Cheng D, Verrier JD, Janesko-Feldman K, Kochanek PM Tags: Am J Physiol Renal Physiol Source Type: research