A specific pattern of gray matter atrophy in Alzheimer's disease with depression - Karavasilis E, Parthimos TP, Papatriantafyllou JD, Papageorgiou SG, Kapsas G, Papanicolaou AC, Seimenis I.

Considering the high incidence of depressive symptoms in Alzheimer's disease (AD), we conducted a large-sample study to investigate the pattern of gray matter (GM) abnormalities that differentiates depressive from non-depressive AD patients. We included 20...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

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Dr. Rita A. Jablonski is one of the most knowledgeable and experienced persons I know when it comes to memory care, dementia and caregivers.I forwarded Rita a question from one of our readers."How Often Should You Visit a Memory Care Patient When They First Go In"?This is an important question, and is often a great source of anxiety for Alzheimer's caregivers.The answer often depends on the actual circumstances at the time.Topic -Memory CareBy Rita A. JablonskiAlzheimer's Reading RoomSubscribe to the Alzheimer's Reading RoomEmail:Hi, Bob.The answer depends on the physical and mental condition of both parties. Som...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer care Alzheimers Dementia care of dementia patients dementia care help alzheimers help dementia memory care nursing home senior care Source Type: blogs
Metallomics Applied to the Study of Neurodegenerative and Mental Diseases. Adv Exp Med Biol. 2018;1055:21-37 Authors: Sussulini A, Hauser-Davis RA Abstract Biochemical imbalances, provoked by aging or a secondary illness, might directly affect the brain, causing severe problems, such as loss of memory or alteration of behavior patterns. Brain disorders are usually classified as injuries (such as stroke, hematomas, and concussions), tumors, and neurodegenerative (such as Parkinson's and Alzheimer's diseases) and mental (such as depression, bipolar disorder, schizophrenia) diseases. As the pathophys...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Publication date: Available online 8 June 2018 Source:Pharmacological Research Author(s): Ester Pagano, Barbara Romano, Angelo A. Izzo, Francesca BorrelliGraphical abstract Highlights The clinical efficacy of curcumin-containing nutraceuticals (e.g. turmeric preparations, curcumin, curcuminoids) for a range of conditions has been assessed by several systematic reviews, in some instances with contradictory conclusions. Our aim was to provide an up-to-date and rigorous synthesis of these data and to evaluate the quality of the available systematic reviews Electronic searches were conducted (up to December 2017) to locate a...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
As I reviewed descriptions of the stages of grief, I realized that Alzheimer ’s and dementia caregivers may go through them as well.Elisabeth K übler-Ross was the author of the groundbreaking bookOn Death and Dying, in which she laid out her theory of the five stages of grief.They are denial, anger, bargaining, depression and acceptance.Subscribe to the Alzheimer's Reading RoomEmail:By Marie MarleyAlzheimer's Reading RoomAs I reviewed descriptions of the stages, I realized that Alzheimer ’s caregivers may go through them as well. I realized that having a loved one living with Alzheimer’s is a kind of...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: acceptance alzheimer's care anger bargaining caregiving dementia care denial DEPRESSION how to grieve stages of grief alzheimer's dementia Source Type: blogs
Publication date: Available online 8 June 2018 Source:Physiology & Behavior Author(s): Mohammad Nasehi, Faezeh Shahini, Mohaddeseh Ebrahimi-Ghiri, Mohammad-Ali Azarbayjani, Mohammad-Reza Zarrindast Chronic stress induces hippocampal-dependent memory deficits, which can be counterbalanced with prolonged exercise. On the other hand, the β-carboline alkaloid harmane exerts potential in therapies for Alzheimer's and depression diseases and modulating neuronal responses to stress. The present study investigated the effect of chronic treatment of harmane alone or during treadmill running on spatial memory deficit in re...
Source: Physiology and Behavior - Category: Physiology Source Type: research
Major depressive disorder in patients aged 70 or older is associated with a poorer prognosis than in younger people Related items fromOnMedica New evidence on benzodiazepine link to Alzheimer ’s Anxiety in midlife linked to risk of later dementia Suicide no more likely in men on 5 α-reductase inhibitors Antidepressants differ in effect on weight gain Doctors debate long-term use of psychiatric drugs
Source: OnMedica Latest News - Category: UK Health Source Type: news
Publication date: August 2018 Source:TrAC Trends in Analytical Chemistry, Volume 105 Author(s): Roopkumar Sangubotla, Jongsung Kim Alzheimer's disease is a progressive neurodegenerative disease that involves loss of memory, thinking, and reasoning and several behavioral characteristics. Alzheimer's disease affects an individual in a drastic manner by exhibiting its impact on the individual's daily routine. A completely accurate diagnosis can be achieved only after the death of a patient by observing the plaques and tangles in the brain. Hence, it is important that researchers develop robust diagnostic tools for detecting ...
Source: TrAC Trends in Analytical Chemistry - Category: Chemistry Source Type: research
Authors: Zhang X, Li L, Chen T, Sun Z, Tang W, Wang S, Wang T, Wang Y, Zhang H Abstract Tonic traditional Chinese medicine is widely used in clinical practice and is categorized into four main drugs, namely, Qi-supplementing, Blood-enriching, Yin-nourishing, and Yang-tonifying. Neurotransmitters play a coordinating role in the nervous system, visceral function, and stress response. The excitation or suppression of the central nervous system is closely related to various diseases, such as insomnia, depression, Alzheimer's disease, Parkinson's disease, and perimenopausal syndrome. An increasing amount of evidence sho...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Abstract Synaptic plasticity is important for maintaining normal neuronal activity and proper neuronal functioning in the nervous system. It is crucial for regulating synaptic transmission or electrical signal transduction to neuronal networks, for sharing essential information among neurons, and for maintaining homeostasis in the body. Moreover, changes in synaptic or neural plasticity are associated with many neuropsychiatric conditions, such as schizophrenia (SCZ), bipolar disorder (BP), major depressive disorder (MDD), and Alzheimer's disease (AD). The improper maintenance of neural plasticity causes incorrect...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
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