Pancreas Bifidum With Acute Necrotizing Pancreatitis Pancreas Bifidum With Acute Necrotizing Pancreatitis
Learn about pancreas bifidum, a rare foregut anomaly, in this unusual case. Does having a bifid pancreas predispose to development of acute pancreatitis?Applied Radiology
Digestive Endoscopy, EarlyView.
Leptin alleviates intestinal mucosal barrier injury and inflammation in obese mice with acute pancreatitis, Published online: 22 June 2018; doi:10.1038/s41366-018-0125-yLeptin alleviates intestinal mucosal barrier injury and inflammation in obese mice with acute pancreatitis
Authors: Zhang WF, Li ZT, Fang JJ, Wang GB, Yu Y, Liu ZQ, Wu YN, Zheng SS, Cai L Abstract The present study aimed to investigate the mechanisms by which mannose protects the lung injury induced in rats with acute pancreatitis (AP). An AP combined with Acute Lung Injury (ALI) model was established. A total of 90 healthy adult male Sprague-Dawley rats (300±50g weight) were randomly divided into three groups: sham operation group (SO group), severe acute pancreatitis lung injury group (SAP group), and mannose intervention group (MT group). Subsequently, each group was divided into two subgroups based on the tim...
We read with interest the systematic review and meta-analysis conducted by Schulman et al1 that measured rates of adverse events in patients assigned to the sham-control arm in published randomized endoscopic intervention trials. The overall rate of serious adverse events was 1.7%, the majority of which were surgery/intensive care unit admission, post-ERCP pancreatitis, and perforat ion. The authors concluded that “investigators should reconsider use of sham-controlled trial designs for endoscopic intervention, while maintaining an emphasis on sound RCT designs.”
Recurrent pancreatitis is a severe complication of Familial Chylomicronemia Syndrome (FCS) mainly secondary to lipoprotein lipase deficiency. The mechanism and interindividual variability of pancreatitis in FCS is not fully understood, but abnormalities in the drainage system of pancreatic veins could be involved.
Authors: Dirks K PMID: 29914614 [PubMed - in process]
This article overviews studies on epidemiology and impact of gastroparesis in the setting of type 1 and type 2 diabetes, with a view to estimating the possible burden of gastrointestinal dysfunction in PPDM. Further, the usefulness of quantifying gastrointestinal dysmotility is discussed. The gastroparesis cardinal symptom index has emerged as a standardised gastrointestinal dysmotility endpoint and its use in individuals after pancreatitis is justified. PMID: 29914234 [PubMed - as supplied by publisher]
A doctor will order a lipase test if they suspect that a person has a problem with their pancreas. When the pancreas is inflamed, it often produces more lipase than usual. If the results of a lipase test show high levels, a person may have pancreatitis. Learn more about lipase levels and how to lower them here.
CONCLUSION: The diagnosis of genetic bisalbuminemia is made by first eliminating the usual acquired etiologies: analytical or drug interference, acute pancreatitis and binding of immunoglobulins. Then, after having checked the lipemic index, reviewed the patient's medical history, comorbidities, and treatments, repeating the electrophoresis will help identify the cause of the bisalbuminemia. PMID: 29914710 [PubMed - as supplied by publisher]
ConclusionThis is the largest study to date examining cannabis use in AP. Cannabis use was found across almost all etiologies of AP with a prevalence of 10% (48 cases), and in 9% (9 cases) of so-called idiopathic AP cases in this cohort, which could account as an association for approximately 2% of all AP cases. Cannabis use did not independently impact AP severity or mortality.