Acute simvastatin treatment restores cerebral functional capillary density and attenuates angiotensin II ‐induced microcirculatory changes in a model of primary hypertension

ConclusionsThe antihypertensive effect of simvastatin is associated with an improvement in cerebral microvascular perfusion and capillary density that may help to prevent hypertension‐induced cerebrovascular damage independent of cholesterol lowering.This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fmicc.12416

Source: Microcirculation - August 1, 2017 Category: Research Authors: Felipe Freitas, Vanessa Estato, Patricia Reis, Hugo C. Castro ‐Faria‐Neto, Vinícius Carvalho, Rafael Torres, Marcos A. Lessa, Eduardo Tibiriçá Tags: Original Research Source Type: research