Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation.

CONCLUSIONS: Vascular endothelial cell migration and permeability change through Akt phosphorylation might be a mechanism of induced fluid retention and peripheral tissue edema by TZD. PMID: 28854981 [PubMed - in process]
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research