Venous thromboembolism and hyperhomocysteinemia as first manifestation of pernicious anemia: a case series

ConclusionsThese reports demonstrate that pernicious anemia, on its own, can lead to hyperhomocysteinemia that is significant enough to lead to thrombosis. Understanding the molecular pathogenesis of the development of thrombosis in patients with hyperhomocysteinemia related to Biermer disease would help us to identify patients at risk and to treat them accordingly. The literature concerning the relationship between homocysteine and venous thrombosis is briefly reviewed.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research