Ethical Challenges in Hematopoietic Cell Transplantation for Sickle Cell Disease: a Review

• Liberal eligibility for SCD matched sibling HCT does not violate ethical principles.• Deferring HCT in childhood until patients can consent is not ethically preferable.• Not offering HCT due to psychosocial concerns may be appropriate.• Minors can serve as donors if necessary safeguards ar e respected.• Preimplantation genetic diagnosis to conceive a matched sibling is an ethical option.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research