Adherence, persistence, and discontinuation among Hispanic and African American patients with multiple sclerosis treated with fingolimod or glatiramer acetate.

CONCLUSIONS: Hispanic and African American patients with MS who initiated FTY had higher adherence than those who initiated GA, similar to the general MS population. These findings suggest that adherence should be considered in DMT selection, and racial/ethnic variations in MS disease course may not be primarily attributable to differences in DMT compliance. PMID: 28857632 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research

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Publication date: Available online 24 May 2020Source: Neurología (English Edition)Author(s): M. León Ruiz, M. Sospedra, S. Arce Arce, J. Tejeiro-Martínez, J. Benito-León
Source: Neurologia - Category: Neurology Source Type: research
Publication date: Available online 24 May 2020Source: Neurología (English Edition)Author(s): A.I. Pérez-Álvarez, P. Suárez-Santos, M. González-Delgado, P. Oliva-Nacarino
Source: Neurologia - Category: Neurology Source Type: research
Publication date: Available online 25 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Charmaine Yam, Daniel Merlo, Jim Stankovich, David Darby, Melissa Gresle, Tomas Kalincik, Trevor J Kilpatrick, Jeanette Lechner-Scott, Bruce Taylor, Michael Barnett, Helmut Butzkueven, Anneke van der Walt
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 24 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Thomas Mathew, Ms Saji K John, Vikram Kamath, Uday Murgod, Kurian Thomas, Anita Angela Baptist, Manjusha Therambil, Asha Shaji, Raghunandan Nadig, Sagar Badachi, Delon D Souza, Sonia Shivde, Amrutha Avati, G R K Sarma, G G Sharath Kumar, Saikanth Deepalam, Gareth J Parry
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 24 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Magdalena Zoledziewska
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Authors: Chan VS Abstract Multiple sclerosis (MS) is an aggravating autoimmune disease that cripples young patients slowly with physical, sensory and cognitive deficits. The break of self-tolerance to neuronal antigens is the key to the pathogenesis of MS, with autoreactive T cells causing demyelination that subsequently leads to inflammation-mediated neurodegenerative events in the central nervous system. The exact etiology of MS remains elusive; however, the interplay of genetic and environmental factors contributes to disease development and progression. Given that genetic variation only accounts for a fraction ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Conclusion: The severity of visual impairment significantly correlated with the severity of axonal loss in affected as well as the fellow eye. NMO is associated with more widespread axonal injury in the affected optic nerve. Hence, RNFL thickness is an indicator of the progression of visual impairment in demyelinating diseases and OCT can help distinguish the etiology and, therefore, may be useful as a surrogate marker of axonal involvement in demyelinating diseases.
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
ConclusionsThe effects of daclizumab beta on clinical and radiologic outcomes were sustained for up to ~  8 years of treatment. No new safety concerns were identified in SELECTED.Trial registrationClinicaltrials.gov NCT01051349; first registered on January 15, 2010.
Source: Journal of Neurology - Category: Neurology Source Type: research
Publication date: Available online 24 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Carotenuto Antonio, Signoriello Elisabetta, Lanzillo Roberta, Vaia Ylenia, Moccia Marcello, Bonavita Simona, Lus Giacomo, Brescia Morra Vincenzo
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 23 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Zeynep Uzdil, Seda Kaya, Pınar Sökülmez Kaya, Murat Terzi, Emre Dünder
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
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