Fibroblast growth factor 15 deficiency increases susceptibility but does not improve repair to acetaminophen-induced liver injury in mice

In this study, treatment of FGF15 knockout (KO) male mice with APAP at 200, 250, or 300mg/kg significantly increased the degree of liver injury compared to wild type (WT) mice.

Source: Digestive and Liver Disease - August 11, 2017 Category: Gastroenterology Authors: Mingxing Huang, Jessica Williams, Bo Kong, Yan Zhu, Guodong Li, Zhe Zhu, Grace L. Guo Tags: Liver, Pancreas and Biliary Tract Source Type: research