Acute Activation of GLP-1-expressing Neurons Promotes Glucose Homeostasis and Insulin Sensitivity

Conclusions We conclude that acute activation of PPG neurons in the brainstem reduces basal glucose production, enhances intraperitoneal glucose tolerance, and augments hepatic insulin sensitivity, suggesting an important physiological role of PPG neurons-mediated circuitry in promoting glycemic control and insulin sensitivity. Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research