Brief primary care intervention cut risky drug use among Latinos by 40 percent

FINDINGSNew research finds that brief interventions in a primary care clinic can reduce patients ’ risky substance use by 4.5 days per month — a 40 percent decline among the Latino patients surveyed — compared with people who did not receive the brief intervention. This corresponds to two fewer weekends of drug use per month, or one less day of use per weekend, or a shorter monthly binge period.BACKGROUNDThe findings duplicate those of the Quit  Using Drugs Intervention Trial, or Project QUIT — conducted by the same research team in 2011 and 2012 — which is aimed at reducing risky drug use. The risky use includes casual, frequent or binge use of illicit drugs, such as cocaine, heroin and methamphetamine, or the misuse of prescriptio n medications, without showing physiological or psychological signs of severe substance use. The trial was conducted in a primary care clinic in East Los Angeles.Previous research demonstrated that a brief intervention by a primary care physician can significantly reduce risky drug use among patients.Subsequent research found that misuse of both prescription and illicit drugs is prevalent enough in Tijuana and East Los Angeles that community clinics in those areas should routinely, though discreetly, screen for it.For this study the researchers took the same principles they used in Project QUIT and applied them in one of the community clinics where they had tested the intervention.METHODThe trial was co...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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CONCLUSIONS: Patients are not always aware of the risk of oral cancer. Accurate information should be provided to patients as well as to specialists rather than just dentists as regard as the risk factors for oral cancer, the importance of referral to specialized departments and timing. The use of new technologies should be widespread. PMID: 32489088 [PubMed - indexed for MEDLINE]
Source: Minerva Stomatologica - Category: Dentistry Tags: Minerva Stomatol Source Type: research
Authors: Thuy LTT, Hai H, Kawada N Abstract Cytoglobin (Cygb), a stellate cell-specific globin, has recently drawn attention due to its association with liver fibrosis. In the livers of both humans and rodents, Cygb is expressed only in stellate cells and can be utilized as a marker to distinguish stellate cells from hepatic fibroblast-derived myofibroblasts. Loss of Cygb accelerates liver fibrosis and cancer development in mouse models of chronic liver injury including diethylnitrosamine-induced hepatocellular carcinoma, bile duct ligation-induced cholestasis, thioacetamide-induced hepatic fibrosis, and choline-de...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
ConclusionsThe optimisation process has facilitated the development and evaluation of a programme that enables the delivery of a promising intervention to achieve weight management in post-menopausal women.Trial registrationISRCTN:ISRCTN11057518. Registered on 21 July 2017. Retrospectively registered.
Source: Trials - Category: Research Source Type: clinical trials
In conclusion, female patients with OSCC were older than male patients with OSCC, and mostly had tumors of the oral tongue. Once patients develop OSCC, there was no difference in survival between men and women in a Taiwanese population.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
We described the risk of hepatocellular carcinoma (HCC, the commonest form of liver cancer originating in the liver) in Danish outpatients with liver cirrhosis due to harmful alcohol consumption. Accurate data on that risk are important for patient counselling and decisions about screening for HCC. The risk was about 0.7% per year, which is lower than might be expected and suggests that many potentially harmful screening examinations are required for every HCC found through surveillance.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
AbstractPurposeThe aim was to analyze the intake of whole grain (WG) and associations with lifestyle and demographics in a newly established cohort of Danish adults.MethodsBetween 2015 and 2019, Danes were enrolled into The Diet, Cancer and Health —Next Generations cohort. A total of 38,553 persons were included in the current cross-sectional study, where all completed a 376-item food frequency questionnaire, a lifestyle questionnaire, and a physical examination in a study center where physical measurements and biological samples were colle cted.ResultsThe median intake of WG was 79  g/10 mega joule (MJ) and 54%...
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
ABSTRACT Objective To assess the outcome of an educational nutritional intervention in the quality of diet of women with breast cancer in adjuvant treatment. Methods Women with breast cancer and admitted for surgical treatment were divided in an intervention group (n=18) and a comparison group (n=78), and participated in a nonrandomized clinical trial. Participants were assessed before and after the treatment and/or intervention. A food frequency questionnaire was applied and the quality of diet was calculated using the Brazilian Healthy Eating Index Revised. The educational nutritional intervention lasted 12 months and wa...
Source: Revista de Nutricao - Category: Nutrition Source Type: research
This study aimed to analyze clinical and laboratory parameters and their association with long-term outcomes in patients who underwent liver transplantation for hepatocellular carcinoma treatment, according to the etiology of the underlying chronic liver disease, in order to identify predictors of response to this therapeutic modality. METHODS: Demographic, clinical, and laboratory data from a cohort of 134 patients who underwent orthotopic liver transplantation for hepatocellular carcinoma treatment at a referral center in Brazil were retrospectively selected and compared according to the etiologic group of the underlying...
Source: Clinics - Category: General Medicine Source Type: research
DiscussionThe results from this review will provide important information about the types of smartphone-based approaches currently available to measure the core behavioural risk factors for chronic disease and the quality of their measurement properties. It will allow recommendations on the most suitable and effective measures of these lifestyle behaviours using smartphones. Valid and reliable measurement of these behaviours and risk factor opens the door to targeted and real-time delivery of health behaviour interventions, providing unprecedented opportunities to offset the trajectory toward chronic disease.Systematic rev...
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Basel, 2 June 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has approved Tecentriq® (atezolizumab) in combination with Avastin® (bevacizumab) for the treatment of people with unresectable or metastatic hepatocellular carcinoma (HCC) who have not received p rior systemic therapy.“We’re excited that today’s approval of Tecentriq in combination with Avastin for unresectable or metastatic hepatocellular carcinoma brings a cancer immunotherapy option to people with this aggressive form of liver cancer,” said Levi Garraway, M.D., Ph....
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
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