Are the Minimal Residual Disease Status and IKZF1 Mutations Play Prognostic Role in Philadelphia-Positive Acute Lymphoblastic Leukemia Patients Treated by RALL Protocols?

Philadelphia –positive acute lymphoblastic leukemia (Ph-positive ALL) have a poor prognosis. Some adverse prognostic features have lost clinical importance with recent improvements in therapy, other such features remain associated with worse outcomes. Different treatment approaches discriminate different risk factors. Molecular factors are researched now as a prognostic.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: Olga Gavrilina, Galina Baskhaev, Bella Biderman, Ksenia Zarubina, Vera Troitskaya, Andrey Sudarikov, Hunan Julhakyan, Elena Parovichnikova Source Type: research