Combinatorial Targeting of Leukemia and Stromal Cells Overcomes Fms-like Tyrosine Kinase 3 (FLT3) Inhibitor Resistance in Acute Myeloid Leukemia (AML)

AML, FLT3-ITD, dual MEK1-FLT3 inhibitor, peptidic CXCR4-antagonist, leukemia-stroma interactions

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: Seemana Bhattacharya, Hong Mu, Sujan Piya, Weiguo Zhang, Teresa McQueen, Linda Paradiso, Galia Oberkovitz, Eyal Benami, Michael Andreeff, Gautam Borthakur Source Type: research