CLL and Fat Cells Utilize Similar Metabolic Pathways

It is assumed that chronic lymphocytic leukemia (CLL) cells originate from B-cells. Yet, unlike their normal counterparts which are resting cells, CLL cells do proliferate. What energy source CLL cells use and which metabolic pathway they recruit to support proliferation is unknown.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: Uri Rozovski, David Harris, Ping Li, Zhiming Liu, Preetesh Jain, Alessandra Ferrajoli, Jan Burger, Phillip Thompson, William Wierda, Michael Keating, Zeev Estrov Source Type: research