Next Generation Chimeric Antigen Receptor (CAR) T Cells

T cells may be genetically modified to express chimeric antigen receptors (CAR) targeted to antigens expressed by tumor cells. We have developed this technology in the laboratory and translated this adoptive T cell approach in the clinic. Recently published reports support the novel approach of treating cancer with patient derived T cells genetically modified to express artificial T cell receptors targeted to tumor associated antigens.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Source Type: research